Meetings/Workshops on Human Physiology and Metabolism in Italy

Conference-Service.com offers, as part of our business activities, a directory of upcoming scientific and technical meetings. The calendar is published for the convenience of conference participants and we strive to support conference organisers who need to publish their upcoming events. Although great care is being taken to ensure the correctness of all entries, we cannot accept any liability that may arise from the presence, absence or incorrectness of any particular information on this website. Always check with the meeting organiser before making arrangements to participate in an event!

Meeting organisers can submit meetings free of charge for inclusion into the listing.

1.
 
Neuroepigenetics and Epitranscriptomics
ID
868405
Dates
19 Aug 2017 - 26 Aug 2017
Location
Siena, Italy
Abstract
Many cellular constituents in the human brain permanently exit from the cell cycle during pre- or early postnatal development, but little is known about epigenetic regulation of neuronal and glial epigenomes during maturation and aging, including changes in cognitive and psychiatric disease. Normal brain development and function is dependent on highly regulated mechanisms governing DNA cytosine methylation and hydroxymethylation, and probably more than 100 residue-specific histone modifications associated with gene expression and silencing and various other functional chromatin states. Equally important is the 3-dimensional organization of the chromosomal material inside the cell nucleus, commonly referred to as the ‘3D Genome’, with chromosomal loopings potentially bypassing hundreds of kilobases on the linear genome to enable promoter-enhancer interactions and other mechanisms important for transcriptional regulation. Combined exploration of epigenomic and 3D genome chromosomal conformation maps maps is likely to illuminate the role of regulatory non-coding sequences in neuropsychiatric disease.
Contact
Francesca Martini;     Phone: [+39.0577.146.0003];     Email: info@nsas.it
Related subject(s)
2.
 
Synaptic and Structural Plasticity
ID
868437
Dates
26 Aug 2017 - 02 Sep 2017
Location
Siena, Italy
Abstract
Different forms of synaptic plasticity occurring at the molecular, cellular and circuit level are the focus of this Advanced Course. The Course will start with critical analysis of the evolution of the study of various forms of long-term potentiation and long-term depression and what is generally accepted about their basic mechanisms, including a discussion of modern approaches to understanding the mechanisms and functions of synaptic plasticity. A wide range of areas will be covered, including: (a) the molecular mechanisms underlying different forms of short-term synaptic facilitation and depression that last no more than a few minutes and are typically mediated by presynaptic mechanisms that alter neurotransmitter release (b) the function of key postsynaptic proteins found in the postsynaptic density as well as the role of neurotransmitter receptor regulation during long-term synaptic and experience-dependent plasticity (c) the methodological approaches that have been recently developed to measure the dynamic localization of synaptic elements at nanoscale resolution and how these nanoscale morphological and functional properties regulate synapses (d) the role of neurogenesis throughout life as a crucial mechanism underlying learning-induced circuits in the dentate gyrus and the olfactory bulb (e) how these forms of plasticity integrate to result in the restructuring of entire neuronal circuits. Participation in the Advanced Course will provide an essential conceptual and methodological framework for anyone intending to pursue rigorous research. The advantages and disadvantages of each method, preparation and recording technique are considered in relation to the specific scientific questions being asked. The Advanced Course will not only develop participants’ skill but will also provide plenty of time for informal gatherings with some of the world leaders in synaptic plasticity, designed to foster brainstorming across different disciplines.
Contact
Francesca Martini;     Phone: [+39.0577.146.0003];     Email: info@nsas.it
Related subject(s)
3.
 
Single Cell Omics
ID
868380
Dates
17 Sep 2017 - 24 Sep 2017
Location
Siena, Italy
Abstract
Neuroscience has entered a critical phase, with several international large-scale efforts devoted to the analysis and understanding of brain function. Studies exploiting new technologies for defining the connections in the brain, driving neuronal activity and modeling of neuronal processing are each hampered by our incomplete knowledge of the brain’s constituent parts. Fortunately, a bevy of single cell analyses are now being deployed to better understand the cells that constitute the functioning nervous system. These approaches offer insights into how cells function individually as the building blocks for understanding how they work in ensemble to create functional pathways. A set of emerging tools are available to assess the molecular and cell biology of single cells, including genomic analyses of somatic mutations, epigenomics to explain the influence of the environment upon genome expression, and transcriptomics to gain insight into the capacity of a cell to synthesize proteins and modulate its environment. Powerful technologies permit a variety of cell constituents to be addressed, including proteins, post-translational modifications, peptides and metabolites. Novel biosensors offer parallel analyses of cellular physiological states, reporting on the pH, membrane voltage and metabolic state. Multiplexed together, such methodologies offer a far more complete biological understanding than the more typical gene expression analyses, providing a rich picture of each single cell’s biology in their normal context – information needed to fully interpret the meaning of results from transcriptomics and proteomics studies.This Advanced Course is designed to provide the foundational knowledge needed to critically evaluate the design and execution of single cell omic studies, through daily lectures by the Faculty, critical reading of papers and extensive didactic discussion sessions. In the sessions, discussion will focus on the proper framing of scientific questions to best utilize these techniques, the limitations and advantages of each technique, and what the data can tell us about neuronal function.
Contact
Francesca Martini;     Phone: [+39.0577.146.0003];     Email: info@nsas.it
Related subject(s)
4.
 
The Neuroscience of Obesity
ID
868390
Dates
17 Sep 2017 - 24 Sep 2017
Location
Siena, Italy
Abstract
Significant progress has been made in recent years in the understanding the role of the nervous system in obesity. Not only several different neuronal pathways, neurotransmitters and hormones have been identified as major players in the regulation of feeding and body weight, bu also energy balance in mammals is controlled by a complex network of interacting feedback mechanisms that involve peripheral organs in addition to higher brain centers. This Advanced Course will provide conceptual- and cutting edge technological framework for state-of-the-art of neuroscience on energy metabolism. The Faculty represents diverse expertise in molecular, cellular, circuit and behavioral approaches on contemporary questions regarding the role of the brain in systemic metabolism regulation and how the periphery affects complex brain functions via neuronal circuits and brain cells.
Contact
Francesca Martini;     Phone: [+39.0577.146.0003];     Email: info@nsas.it
Related subject(s)

View all listed conferences in Italy.

Good to know...

You can advertise your event or services in this space.

Last updated: 07 January 2017