This SRC is an important and unique scientific conference where the pivotal role of TGF-β family members, including TGF-βs, nodal, activins, BMPs, and GDFs, in developmental, homeostatic, and pathological processes is explored through formal talks, poster sessions, and interactive and intensive scientific discussion sessions. Expansion of this field into previously uncharted areas of biology and human pathogenesis is exemplary, and in part, due to high throughput efforts that serendipitously bring scientists to the world of TGF-β. Program topics include tissue morphogenesis in development and disease, signaling networks and crosstalk, inflammation, vasculature and tissue transformation, tissue microenvironment dynamics in disease, therapeutic frontiers of TGF-β signaling, and homeostatic and metabolic control of growth and disease. This conference will seek to strengthen interactions between those scientists studying molecular mechanisms and those studying development and disease, and will welcome scientists who recently entered the TGF-β field. The conference program planned so far is truly global and represents the breadth of TGF-β family biology. A significant number of submitted abstracts will be selected for short talks. The oral presentations together with three poster sessions and the recreational afternoon sessions will ensure a good blend between young and more advanced investigators, students and postdoctoral fellows that can use this time productively towards building collaborations and scientific exchanges.