Conférences  >  Sciences biologiques  >  Biologie moléculaire  >  États-Unis

Lipids are essential for plant growth, development, and environmental adaptation and serve as important renewable sources of food, feed, biofuel, and industrial feedstocks. Plant lipids are also at the core of our energy economy, as lipids form the photosynthetic membranes and neutral storage lipids represent an energy-dense reservoir of reduced carbon and fuel. These benefits, which are critical to human society, underscore the importance of understanding how lipids are produced and function within plants. It is the goal of the 2023 meeting to bring together visionary leaders, stakeholders, and academic scientists to discuss the latest findings and technological advances in basic lipid research and identify how these discoveries can be leveraged to create new opportunities for human benefit.

Using Basic Plant Lipid Science to Drive Functional Changes for Human Benefit

Interrogating and Connecting Cell-Matrix Interactions Across Length Scales

Mechanisms and Consequences of Genome Instability

Biologie,    Génomique et bio-informatique

Exposures to environmental and endogenous DNA damaging agents produce thousands to over a million DNA lesions and chemical modifications to the genome per cell every day. Perturbations in the cellular pathways that respond to DNA damage are linked to myriad human diseases across nearly every cell and organ type. Conversely, dysfunction in DNA damage responses presents new vulnerabilities that are being leveraged to selectively target tumors in a more efficacious and less toxic manner. This GRC will bring together researchers at all levels including principal investigators, lead scientists, postdoctoral fellows and graduate students from academia, government and industry, to share and discuss the latest cutting-edge research on mechanisms of genome maintenance and roles in human health.

Genome Maintenance: From Molecules and Mechanisms to Humans and Therapies

Biologie,    Génomique et bio-informatique

Studies of the fundamental process of translating mRNA into a protein sequence have greatly advanced our understanding of underlying molecular mechanisms and in consequence their regulation and disease association. Research on mRNA translation involves a wide spectrum of methods from single molecule measurements to the phenotypical characterization of organisms. This GRS will provide a platform where young scientists investigating different aspects of protein synthesis can meet for discussions about experimental approaches, exchange ideas and start collaborations, as well as obtain advice on possible career paths.

Exploring Protein Synthesis from Molecule to Organism

The well-studied process of mRNA translation is fundamental to all biology, and the relevance of this process to disease is emerging rapidly. The 2023 Gordon Research Conference (GRC) on Translational Machinery in Health and Disease will provide a unique forum for both new and established investigators to discuss their latest findings on the relationship of protein synthesis to disease. This interdisciplinary conference will cover connections between translation and a broad range of diseases including cancer, neurological, metabolic, inflammatory, infectious, and mitochondrial disorders. Scientific sessions will highlight recent discoveries on the genetic and molecular disturbances of translation that underlie pathophysiology. Other talks will focus on new technologies to study translation, translation during stress, in pathogens, and in the microbiome. A major goal of this conference will be to foster interactions among scientists at all levels to stimulate data exchange and collaborations across disciplines. Ample time will be provided for formal discussions during the scientific sessions and time will also be set aside for informal discussions. Poster presentations as well as the selection of speakers from submitted abstracts will ensure participation from investigators at all stages of their career. In addition, this GRC will be preceded by a Gordon Research Seminar (GRS) on Translational Machinery in Health and Disease which will be open only to students and postdoctoral fellows. The GRS will complement the GRC and provide a forum for trainees from around the world to broaden their peer network and to explore new directions in translation research.

Protein Synthesis and Cellular Synergy

Cambridge Healthtech Institute

Join thousands of international thought leaders to discuss the latest research, technologies, innovation and business models in implementing precision medicine, biomarkers and companion diagnostics, genomic medicine, and precision health; innovation and market access strategies for at-home diagnostics, point-of-care testing and molecular diagnostics for infectious diseases; liquid biopsy and advanced diagnostics for precision oncology, including Multi-Cancer Early Detection and Minimal Residual Disease testing; and emerging technologies for spatial biology and single-cell multiomics.

Ethan Bell;     Tél.: [7812476254];     Email.: ebell@healthtech.com

CHI

For almost 3 decades, the Molecular & Precision Med TRI-CON has served as the leading international meeting place for the diagnostics and precision medicine community. As we celebrate the 30th Anniversary and look forward to in-person networking, Cambridge Healthtech Institute once again takes the leadership role of bringing together the life science community at the TRI-CON 2023. Join thousands of international thought leaders to discuss the latest research, technologies, innovation and business models in implementing precision medicine, biomarkers and companion diagnostics, genomic medicine, and precision health; innovation and market access strategies for at-home diagnostics, point-of-care testing and molecular diagnostics for infectious diseases; liquid biopsy and advanced diagnostics for precision oncology, including Multi-Cancer Early Detection and Minimal Residual Disease testing; and emerging technologies for spatial biology and single-cell multiomics. The new track on Digital Medicine reflects the future of precision medicine and adds coverage of artificial intelligence, digital diagnostics and digital biomarkers, digital pathology, sensors and wearables. Join us in sunny San Diego for the in-person networking you’ve come to expect from the TRI-CON and special 30th Anniversary keynotes. Don’t miss a minute of the cutting-edge 10-track scientific program with convenient on-demand viewing.

Email.: chi@dryfta.com

The Glycobiology GRS is a small group setting that fosters open discussion of innovative glycobiology research through formal presentation and social interaction. The seminar will include three scientific session and two poster sessions. The seminar will highlight recent progress in understanding the functional role of glycans and glycoconjugates in a range of areas including (although not limited to): cell signaling, host-pathogen interactions, immune regulation, development, genetic disease, neurobiology and cancer. Emerging methodologies for glycan synthesis, structural glycan analysis and glyco-informatics will also be discussed. The seminar will conclude with a career panel session during which mentors at various stages of their careers will share experiences and answer questions from trainees focused on professional development and other topics.

Mapping the Functional Glycome in Health and Disease

The Glycobiology GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.

Biological Roles of Glycans as Major Building Blocks of Life

The focus of the 2023 GRS is epitranscriptomics, RNA and DNA editing and modifications. These modifications are highly abundant and naturally occurring in nearly all organisms. The GRS on RNA editing brings together graduate student and post-docs to discuss fundamental mechanisms of these modifications and their aberrations in health and disease. The GRS will have two poster sessions and oral talks will be selected from submitted abstracts. The synergistic arrangement of the GRS and GRC will provide multiple opportunities for trainees to build professional networks and foster scientific collaborations.

Diverse Roles of Nucleic Acid Modifications: Biological and Technological Advances in Health and Disease

Biotechnologie,    Génomique et bio-informatique

Over the last decade or so, the field of quantum biology has been propelled by experimental and theoretical efforts that have led to remarkable discoveries at the interfaces of traditional disciplines (e.g., biology, chemistry and physics). Evidence suggests that subtle quantum effects may shape biological processes and functions in living organisms, as exemplified by photosynthesis, enzyme catalysed reactions, and magnetic field effects on spin-dependent reactions in biology, to name a few. This is an exciting and emerging science of the 21st century, where there are many fascinating, fundamental questions that will inspire new ways to better understand and enhance health and medicine.

Emerging Methodologies to Investigate Quantum Effects in Biology

Mécanique quantique et l'information quantique,    Chimie physique, Chimie informatique

The 2023 meeting is subtitled: “RNA/DNA editing and epitranscriptomics across biological systems”. Modifications to the common nucleosides found in DNA and RNA have been known for many years. However, recent advances in analytical techniques for their detection, along with a deeper understanding of the broad impact these modifications have on fundamental biological processes, including human disease, have caused a renaissance in their study. Indeed, we now know that nucleic acid modifications are common in various naturally occurring nucleic acids and influence gene expression, protein synthesis, cognition, innate and adaptive immunity, autoimmune disease and cancer. This meeting will bring together a diverse group of scientists with varying expertise with the common goal of sharing ideas and approaches that can advance our understanding of the many facets of nucleic acid modifications.

RNA and DNA Editing and Epitranscriptomics Across Biological Systems

Biotechnologie,    Génomique et bio-informatique

This highly dynamic field combines theoretical, computational, biochemical, physical, and cellular approaches to understand the molecular mechanisms that shape life. The 2023 GRS meeting will focus on recent advances in these areas, which have allowed a better understanding of how proteins shape and power biology. Topics will include protein folding, binding interactions, allostery, evolution, design, cellular signaling, macromolecular organization, and more.

Combining Theory and Experiments to Understand Mechanisms of Function

Launched in 2007, this cross-disciplinary FASEB Science Research Conference (SRC) is focused on endoplasmic reticulum (ER) function and dynamics, and the contribution of ER dysfunction to disease.  The conference brings together cell biologists and disease-oriented researchers, including both trainees and independent investigators. It attracts basic researchers interested in protein folding, protein secretion, cellular stress responses, protein post-translational modification, proteasome dependent protein degradation, and regulation of lipid biosynthesis, as well as researchers focusing on a range of pathologies, including diabetes, neurodegeneration, cancer, and diseases of protein misfolding.

Protein science is continuing a dramatic renaissance with the emergence of ever-more powerful methods of structural biology, computation, and molecular biology. The arena of practical applications of protein science continues to expand explosively. The 2023 Proteins GRC will highlight “complexity in proteins” by bringing together experimental, theoretical and computational biochemists, biophysicists, chemists, chemical biologists, biologists and bioengineers who study the diverse aspects of protein science including protein function, dynamics, thermodynamics and structure using cutting-edge techniques and strategies.

Complexity in Proteins

Understanding the molecular mechanisms of gene expression regulation and their implications in drug development/medicine will be the general theme of the 2023 Nucleic Acids GRS. The meeting will also serve as a platform to discuss recent technical developments in cutting-edge microscopy and next generation sequencing methods employed by nucleic acid researchers.

Mechanism Meets Medicine

The Nucleic Acids Gordon Research Conference (NAGRC) is the premier meeting for exchange of new ideas about the structure and mechanistic behavior of nucleic acids and their cellular processing factors, and the potential applications of innovative developments in RNA and DNA science. Historically, the meeting has provided a powerful forum for synthesizing cutting edge information that leads to ground-breaking discoveries and world-changing technologies. An important feature of the meeting is the inclusion of late-breaking findings and the active participation of early career scientists who are at the forefront of nucleic acid science.

Structural, Functional and Mechanistic Behavior of DNA, RNA and Nucleic Acid Processing Enzymes

The focus of this meeting is to highlight advances in the field of nucleosides, nucleotides, and oligonucleotides. Speakers will discuss chemical biology, synthesis, structure, and therapeutic applications of natural and engineered small molecules and oligomers.

Chemical Biology and Clinical Applications of Nucleosides, Nucleotides and Oligomers

Polyamines in Cancer, Medical Genetics, Aging, Pathogens and Plants

For many years, nucleos(t)ide analogues and nucleic acids have served as cornerstones of drug design and development efforts. The Nucleosides, Nucleotides and Oligonucleotides (NNO) Gordon Research Conference is dedicated to understanding the fundamental chemistry, biology, and technologies for the diagnosis and treatment of various diseases using nucleos(t)ides and nucleic acid analogues. In recent years nucleic acids have seen wide use in chemical biology investigations as well as in the clinic as therapeutics and diagnostics. Emerging areas like CRISPR gene editing and siRNA have been developed due to the extensive efforts of many in the NNO field. The 2023 edition will be the 21st NNO GRC and will reflect the evolution of the field and the current explosive growth of NNO based therapeutics, from its original focus on purine and pyrimidine chemistry and biology, to the much broader current scope.

Chemical Biology of Nucleosides and Nucleic Acids Towards Human Therapeutics

Pharmacologie et développement des médicaments,    Biochimie et chimie médicale, toxicologie

UC Santa Barbara, Kavli Institute for Theoretical Physics (KITP)

A long-standing question in the neurobiology of learning is that of timescales. The brain can associate events that are separated by seconds, minutes, hours, days, weeks, or longer. Yet, the known biological mechanisms for inducing changes in the synaptic connections between neurons are driven by neural events that are separated by typically no more than a few tens or hundreds of milliseconds. This conference will convene scientists studying the molecular, cellular, and circuit-level mechanisms used by the brain to bridge the multiple timescales across which events play out in the experience of an individual. The goal will be to assemble an up-to-date understanding of the set of biological mechanisms available in the brain to support associative learning across different timescales. The conference's emphasis on biological mechanisms will complement and support the main program’s more computational focus, and encourage an integrated analysis of statistical learning spanning molecular, cellular, circuit, and behavioral-level phenomena.

Réseaux de neurones et intelligence artificielle, apprentissage automatique,    Neurologie

Cell Biology and Signalling

BPS - The Biophysical Society

A vast number of biologically important enzymes, transporters, and other molecules require the participation or transport of protons. Because the proton is unique in many respects, its properties and reactions are often quite distinct from those of other ions. Our goal is to include a truly international spectrum of speakers and attendees. The invited speakers include chemists, structural biologists, and physiologists whose expertise encompasses a wide range of topics that are all related to the proton. We hope to encourage new understandings on levels from basic science to biomedical applications.