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1
Training — Understanding Polymorphism and Crystallisation Issues in the Pharmaceutical Industry
13. Feb 2023 - 17. Feb 2023 • Online Platform, Virtuelle Veranstaltung
Veranstalter:
Scientific Update Ltd.
Zusammenfassung:
5 sessions aim to give chemists and chemical engineers a thorough practical knowledge of crystallisation processes. After an introduction the course will cover crystallisation of compounds (including hydrates and solvates), different methods of crystallisation, polymorphism, salts and co-crystals, crystallisation of chiral compounds and classical resolution, analytical methods for studying the solid state and will finish with some case studies. Real life practical examples will be used throughout the course to exemplify the different aspects of crystallisation and polymorphism. The course will cover all aspects of the subject including crystallization of intermediates as well as final products. In addition, precipitations and amorphous solids will be covered and the differences between amorphous solids and crystalline solids will be discussed.
Eintrags-ID:
1512476
2
Training — Design, Development and Scale-Up of Safe Chemical Processes and Operations
20. Feb 2023 - 24. Feb 2023 • Online Platform, Virtuelle Veranstaltung
Veranstalter:
Scientific Update Ltd.
Zusammenfassung:
This seminar is designed to enhance the awareness of chemists and engineers regarding hazard issues. Utilising the expertise of the chemists and chemical engineers at DEKRA and Scientific Update, it will consider hazard control of new chemical processes throughout their development cycle: from early development through to full-scale production. Hazards can often be eliminated by appropriate choice of reagent or synthetic route at the R&D stage. Where this is not possible, techniques exist to quantify the hazards so that robust engineering solutions can he applied in production.
Eintrags-ID:
1512486
3
Training — Work Up and Product Isolation – Short Course
23. Feb 2023 - 24. Feb 2023 • Online Platform, Virtuelle Veranstaltung
Veranstalter:
Scientific Update Ltd.
Zusammenfassung:
This short course will discuss the importance of designing simple, practical reaction quenches, work-ups and product isolations for a range of reaction and product types e.g. highly exothermic quenches, products with poor stability, removal of reagent by-products, consideration of impurities and meeting the needs of process intermediates as well as final products. The focus of this short course will be to design processes suitable for large scale operation and the importance of laboratory experimental design and execution to adequately model the large-scale process.
Eintrags-ID:
1512430
4
Training — Filtration and Drying Course
20. Mär 2023 - 22. Mär 2023 • Online Platform, Virtuelle Veranstaltung
Veranstalter:
Scientific Update Ltd.
Zusammenfassung:
Filtration and drying are the essential but unsung heroes of whole process design: this 3 x 3-hour session course will guide you through the underlying principles you need to consider to successfully implement them during product commercialisation.
Eintrags-ID:
1512559
5
Training — Practical Management of Impurities and Development of Effective and Comprehensive Control Strategies
21. Mär 2023 - 29. Mär 2023 • Online Platform, Virtuelle Veranstaltung
Veranstalter:
Scientific Update Ltd.
Zusammenfassung:
This Online course is aimed at providing a holistic understanding of the challenges and issues associated with implementing an effective control strategy for all impurity types. It will examine key areas, specifically, impurity qualification, mutagenic impurities, elemental impurities, extractives and leachables and solvents. In each case, it will examine practical approaches through both case studies and practical exercises and in all instances provide clarity as to the current and emerging regulatory frameworks.
Eintrags-ID:
1512536
6
Training — Biocatalysis as a Tool for the Synthetic Chemist
27. Mär 2023 - 30. Mär 2023 • Online Platform, Virtuelle Veranstaltung
Veranstalter:
Scientific Update Ltd.
Zusammenfassung:
The aim of the course is to give organic chemists an understanding and an overview of the subject of biotransformations.
Eintrags-ID:
1512568
7
Training — Understanding Process Plant Cleaning for More Efficient Changeovers
17. Apr 2023 - 19. Apr 2023 • Online Platform, Virtuelle Veranstaltung
Veranstalter:
Scientific Update Ltd.
Zusammenfassung:
The course objective is to enable participants to understand the fundamental science and engineering principles underlying process plant cleaning performance and will be covered over 3 x 3-hour sessions, combining extensive input from the course tutor, Britest Senior Innovation Specialist Rob Peeling, with ample opportunities for interactive discussion and exploration of common issues and shared experiences with fellow online trainees.
Eintrags-ID:
1512555
8
Training — Safety & Selectivity in the Scale-Up of Chemical Reactions
17. Apr 2023 - 20. Apr 2023 • Online Platform, Virtuelle Veranstaltung
Veranstalter:
Scientific Update Ltd.
Zusammenfassung:
This is an almost unique course on the safety of chemical reactions and processes that are designed by chemists for chemists (and engineers) with the ultimate aim of helping the chemical industry reduce the number of chemical or process related incidents.
Eintrags-ID:
1512490
9
Training — Scale-Up: What Goes Wrong? Short Course
24. Apr 2023 - 25. Apr 2023 • Online Platform, Virtuelle Veranstaltung
Veranstalter:
Scientific Update Ltd.
Zusammenfassung:
This is an Online Short Course and will look at the reasons why reactions don’t always scale-up as expected, using real-life examples from industry. The course will be in two sections of 60-90 minutes held over two consecutive days.
Eintrags-ID:
1512554
10
Training — Design of Experiments for Chemists and Engineers
08. Mai 2023 - 11. Mai 2023 • Online Platform, Virtuelle Veranstaltung
Veranstalter:
Scientific Update Ltd.
Zusammenfassung:
Industrial Scientists can no longer afford to experiment in a trial-and-error manner, changing one factor at a time. A far more effective method is to apply a systematic approach to experimentation that considers all factors simultaneously. This approach is called Design of Experiments (DoE) and many scientists use it as an efficient way to solve serious problems afflicting their projects. DoE provides information about the interaction of factors and the way the total system works, something not obtainable through traditional testing methods. DoE also shows how interconnected factors respond over a wide range of values, without requiring the testing of all possible values directly. DoE is a fundamental aspect of Quality by Design.
Eintrags-ID:
1512607
11
Training — Secrets of Batch Process Scale-Up
08. Mai 2023 - 12. Mai 2023 • Online Platform, Virtuelle Veranstaltung
Veranstalter:
Scientific Update Ltd.
Zusammenfassung:
This course is designed for those with limited or no pilot plant or scale-up experience, provides a comprehensive overview of the most common problems experienced during the scale up of laboratory batch processes, and ways to avoid or mitigate them. The difference between laboratory scale techniques and how the major unit operations are carried out in the pilot plant is a key focus of the course. Thus, along the way attendees will examine the many issues associated with raw material handling, conducting synthetic reactions, reaction workup, product crystallization, isolation and drying at the pilot plant or commercial scale.
Eintrags-ID:
1512608
12
Training — Solvents and Solvent Selection in Chemical Manufacturing
15. Mai 2023 - 17. Mai 2023 • Online Platform, Virtuelle Veranstaltung
Veranstalter:
Scientific Update Ltd.
Zusammenfassung:
This is a ONLINE short course which will look at reducing the burden of solvents, importance of solvent selection, and how to reduce solvent use and select solvents with a better safety and environmental profile.
Eintrags-ID:
1512595
13
Course — An Introduction to Chemical Engineering Science
12. Jun 2023 - 15. Jun 2023 • Online Platform, Virtuelle Veranstaltung
Veranstalter:
Scientific Update Ltd.
Zusammenfassung:
This course has been developed, and is presented, by chemical engineers and chemists who specialise in facilitating knowledge transfer and understanding between different scientific and engineering disciplines working at the R&D-manufacturing interface. As a result, it does not dwell on the derivation of mathematical formulae or equations used in chemical engineering design, but instead focuses on what other disciplines need to know about the information and data that chemical engineers require for design, scale-up and process troubleshooting.
Eintrags-ID:
1538953
14
Course — Biocatalysis – Solving Scale-Up Issues with Biocatalysed Reactions
19. Jun 2023 - 20. Jun 2023 • Online Platform, Virtuelle Veranstaltung
Veranstalter:
Scientific Update Ltd.
Zusammenfassung:
Many forays by organic chemists into using biocatalysis in chemical synthesis stall at the initial scale-up stage. Screening and small scale (gram) reactions progress as planned, but when scaled -up, reactions stall, take more enzyme than expected, work-ups end up with emulsion issues etc. This course will look at some of the techniques and technologies ( tricks of the trade) that can help derisk scaling up biocatalysed reactions .A further barrier to the adoption of more biocatalytic reactions are production / EHS scientists who are unsure how to handle enzymes in the plant/pilot plant. the course will also look at good sources of information/data to facilitate the use of enzymes at scale.
Eintrags-ID:
1538930
15
Course — Fluid Transfer and Liquid Mixing Short Course
26. Jun 2023 • Online Platform, Virtuelle Veranstaltung
Veranstalter:
Scientific Update Ltd.
Zusammenfassung:
This VIRTUAL short course has been developed, and is presented, by chemical engineers and chemists who specialise in facilitating knowledge transfer and understanding between different scientific and engineering disciplines working at the R&D-manufacturing interface. They do not dwell on the derivation of mathematical formulae or equations used in chemical engineering design, but instead focuses on what other disciplines need to know about the information and data that chemical engineers require for design, scale-up and process troubleshooting.
Eintrags-ID:
1538950
16
Course — Quality by Design in Pharmaceutical Development
26. Jun 2023 - 30. Jun 2023 • Online Platform, Virtuelle Veranstaltung
Veranstalter:
Scientific Update Ltd.
Zusammenfassung:
Participants will learn how to identify and prioritise process parameters, determine and manage risk, and implement control strategies. The use of experimental design (DoE) in QbD, the identification of potential mixing and scale-up problems, and the safe scale up of processes to pilot and manufacturing plants will also be discussed.
Eintrags-ID:
1539037
17
Course — Chemical Development & Scale-Up in the Fine Chemical & Pharmaceutical Industries
10. Jul 2023 - 17. Jul 2023 • Online Platform, Virtuelle Veranstaltung
Veranstalter:
Scientific Update Ltd.
Zusammenfassung:
This three-day course, written and presented by highly experienced process chemists from the pharmaceutical and fine chemical industry, provides a comprehensive foundational overview of this fascinating and important element of the chemical industry. A logical investigative approach to all aspects of chemical development is described, with an abundance of case studies from literature, conferences and private communications.
Eintrags-ID:
1539087
18
Course — Physical Organic Chemistry Concepts for Process Scale-Up
11. Sep 2023 - 13. Sep 2023 • Online Platform, Virtuelle Veranstaltung
Veranstalter:
Scientific Update Ltd.
Zusammenfassung:
Based on the work of Prof John Atherton, this course provides an introduction to some of the key physical organic chemistry principles that underpin chemical process development as well as the requirement for inter-disciplinary cooperation i.e. process development chemists, chemical engineers, analytical chemists etc.
Eintrags-ID:
1539119
19
Course — Scale-Up: What Goes Wrong? Short Course
18. Sep 2023 - 19. Sep 2023 • Online Platform, Virtuelle Veranstaltung
Veranstalter:
Scientific Update Ltd.
Zusammenfassung:
This is an Online Short Course and will look at the reasons why reactions don’t always scale-up as expected, using real-life examples from industry.
Eintrags-ID:
1539118
20
Course — Applied Mixing Technology for Process Development: Scaling Down to Scale Up
03. Okt 2023 - 06. Okt 2023 • Online Platform, Virtuelle Veranstaltung
Veranstalter:
Scientific Update Ltd.
Zusammenfassung:
Use of the proper mixing technology is often essential for successful process results. This online course considers how we can choose appropriate mixing conditions for laboratory, pilot, and commercial scale units to ensure technical success. The course begins by rooting us in some essential basics of mixing technology. With those fundamentals, we then progress through different mixing applications in increasing levels of complexity: single-phase (blending and heat transfer), multiple phase (solid-liquid, immiscible liquid, gas-liquid, and 3-phase), and mixing in competitive rate processes (reactions and crystallizations). Throughout, we look at scale-up and scale-down by using examples from industrial processes which have a variety of mixing requirements. We will discuss how to design and execute practical experiments at the small scale which can identify mixing sensitivities in a process that could be an issue on scale-up. Though primarily focusing on operations in stirred tanks, we will also discuss mixing applications in flow systems like static mixers.
Eintrags-ID:
1539138
21
Course — Green Chemistry – Towards More Sustainable Synthesis
09. Okt 2023 - 10. Okt 2023 • Online Platform, Virtuelle Veranstaltung
Veranstalter:
Scientific Update Ltd.
Zusammenfassung:
This Online short course on “Towards more sustainable synthesis” will look at techniques, strategies and tools to minimise the environmental impact of manufacturing pharma/agrochemical & fine chemical intermediates and products.
Eintrags-ID:
1539092
22
Course — Chemical and Process Safety for Development Chemists
09. Okt 2023 - 17. Okt 2023 • Online Platform, Virtuelle Veranstaltung
Veranstalter:
Scientific Update Ltd.
Zusammenfassung:
In this course, the basics of chemical process safety are explained, always starting from the underlying chemistry. A lot of emphasis will be put on heat and gas evolution, how they affect the inherent process safety and how they can be measured in the lab. Basic scale-up calculations for both gas and heat evolution will be explained using examples and exercises. Guidelines will be given to prevent possible issues with heat transfer at larger scale. The importance of stability data of chemicals, reaction mixtures and products will be explained, together with different tools to determine them experimentally. Background will be provided to understand and interpret the results of reaction calorimetry and thermal stability experiments. Safety aspects of upstream or downstream processes like storage and waste streams will be discussed. The safety benefits of flow chemistry will be explained, and the specific safety evaluation needed for such flow processes will be explored as well.
Eintrags-ID:
1539168
23
Course — Design of Experiments for Chemists and Engineers
13. Nov 2023 - 16. Nov 2023 • Online Platform, Virtuelle Veranstaltung
Veranstalter:
Scientific Update Ltd.
Zusammenfassung:
The Course will empower Scientists to implement DoE in their work to more efficiently improve their processes.
Eintrags-ID:
1539218


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Stand vom 19. Januar 2023