Konferenzen  >  Chemie  >  Biochemie und Medizinische Chemie, Toxikologie

Scientific Update Ltd.

The aim of this course is to provide attendees with a good basis to work from when involved in taking development candidates to the first in human trials with a view also on some longer-term requirements.  The course content will therefore focus on the necessary early phases of chemical development as would typically be required to support production of up to about 2kg using laboratory-based 20L equipment and pilot plant equipment.

Berufliche Weiterbildung für Chemiker,    Pharmakologie und Arzneimittelentwicklung

University of Ioannina, Epirus, Greece

Organometallchemie, Koordinationschemie,    Organische Chemie und Polymere

The focus of this meeting is to highlight advances in the field of nucleosides, nucleotides, and oligonucleotides. Speakers will discuss chemical biology, synthesis, structure, and therapeutic applications of natural and engineered small molecules and oligomers.

Chemical Biology and Clinical Applications of Nucleosides, Nucleotides and Oligomers

Since the first International Hydrogenases Conference held in Szeged, Hungary in 1985, these successful meetings have been held every three years. As in the previous Hydrogenases Conferences, all fronts of fundamental and applied reseach on hydrogenases are covered in the scientific program, ranging from microbiology to chemical synthesis of biomedical compounds. Additionally, research on related redox (bio) catalysts for energy conversion, such as formate dehydrogenases, CO-dehydrogenases, and photosystems, is included within the scope of the conference

European Molecular Biology Organization – EMBO

For many years, nucleos(t)ide analogues and nucleic acids have served as cornerstones of drug design and development efforts. The Nucleosides, Nucleotides and Oligonucleotides (NNO) Gordon Research Conference is dedicated to understanding the fundamental chemistry, biology, and technologies for the diagnosis and treatment of various diseases using nucleos(t)ides and nucleic acid analogues. In recent years nucleic acids have seen wide use in chemical biology investigations as well as in the clinic as therapeutics and diagnostics. Emerging areas like CRISPR gene editing and siRNA have been developed due to the extensive efforts of many in the NNO field. The 2023 edition will be the 21st NNO GRC and will reflect the evolution of the field and the current explosive growth of NNO based therapeutics, from its original focus on purine and pyrimidine chemistry and biology, to the much broader current scope.

Chemical Biology of Nucleosides and Nucleic Acids Towards Human Therapeutics

Molekularbiologie,    Pharmakologie und Arzneimittelentwicklung

Scientific Update Ltd.

Medicinal chemists need to understand the relationship between chemical structure and the physical properties of molecules and how this translates into compound stability and the interaction of the molecule with biological structures. These biological targets include proteins, lipids, nucleic acids and cell membranes. Interaction of the molecules with these targets affects the distribution of the compound in biological systems and modulates biological function. To do this successfully the medicinal chemist needs to be aware of how target selection is carried out and how this effects lead generation. The medicinal chemist needs knowledge of structure property relationships, the physico-chemical properties of drugs and how these molecules interact with the body– pharmacokinetics and ADME (Absorption, Distribution, Metabolism and Excretion).

Learn from global experts from academia and industry who will share the latest advances in organic chemistry, chemical biology and medicinal chemistry.

The conference will cover all aspects of the molecular roles of metal ions in human health and disease and in the pharmaceutical and imaging sciences, as well as connections to related fields such as environmental and nutrition sciences.

American Association for Clinical Chemistry

Industrielle Chemie und grüne Chemie,    Analytische Chemie, Anorganische Chemie

Industrielle Chemie und grüne Chemie,    Analytische Chemie, Anorganische Chemie

The conference is organized jointly by the Institute of Physical Chemistry, Polish Academy of Sciences (IChF) in Warsaw, and the Laboratory of Chemistry and Biology of Metals (LCBM), French Alternative Energies and Atomic Energy Commission (CEA).

The 2023 conference follows the previous QBIC meetings in Warwick (1999), Lund (2003), Český Krumlov (2011), Bath (2018), and Marseille (2019). QBIC-VI is the third meeting organized since the founding of the Quantum Bioinorganic Chemistry Society. The scientific focus of the conference is on computational inorganic and bioinorganic chemistry, covering theoretical methods, novel applications, and combined computational/experimental approaches. We are proudly supported by the Candela Foundation.

Physikalische (theoretische) Chemie, Chemoinformatik,    Analytische Chemie, Anorganische Chemie

Planned topics include new developments of computational approaches in biochemistry and biophysics, applications of quantum chemical methods on molecular models, modeling interaction in molecular materials, modeling new molecular materials, drug design molecular dynamics, Monte Carlo and molecular mechanics simulations in biodisciplines.

This workshop focusses on the modelling and mechanistic questions related to bidirectional catalysis. Whereas many catalysts work in the two directions of the reaction, bidirectional synthetic molecular redox catalysts are scarce. In enzymology, there has been much interest in trying to elucidate what makes a particular enzyme faster in one direction (a property sometimes called the “catalytic bias”). Related to this question is how much free energy is required to kick off catalysis and what makes the so-called “reversible catalysts” function at a fast rate even close to equilibrium, a property that is needed to design energy efficient devices. Examining experimentally the relations between catalytic rate and driving force is more difficult with a biological motor than with a molecular or a surface redox catalyst, but the same concepts apply. This workshop aims at bringing together people from different fields (surface catalysis, molecular catalysis, molecular machines) to clarify the overlaps, see how much knowledge can be transferred across disciplines, and describe recent advances in the use, design, benchmarking and kinetic modeling of bidirectional catalysts.

Analytische Chemie, Anorganische Chemie,    Elektrochemie, Elektrolyse und Korrosion

Uventia Global

Highly potent active pharmaceutical ingredients, or HPAPIs, are potent compounds that could effectively treat serious and life-threatening diseases such as cancer. Because of their high potency, these substances eventually put the workers in the production facility at risk. While exceptional product quality is required, additional measures must be taken to ensure operator safety. At our online meeting, leading figures from the industry, occupational toxicologists and containment specialists will review the most recent developments affecting the handling of HPAPIs. The discussion will center on the safe and effective processing of potent APIs, process development and scale-up, occupational health hazards, toxicological assessment, improvements in isolators and facilities to minimize exposure risk, containment and cleaning validation practices, and risk management for cross-contamination.

Email: yuliia.terletska@uventia.com

HPAPI, API, Compounds Manufacturing, Occupational Toxicology, Industrial Hygiene, Process Engineering, Process Development, Containment, Cross Contamination, Cleaning Validation, Cleanroom, Risk Management, Quality Assurance, Quality Control, Analytical Development, Analytical Methods, Outsourcing

Biotechnologie,    Pharmakologie und Arzneimittelentwicklung

International Union of Pure and Applied Chemistry (IUPAC)

ISCNP31 & ICOB11 is a fantastic opportunity to meet leading scientists from all over the world providing their contribution on various aspects and applications of this long tradition and fascinating area of research of chemistry of natural products and biodiversity science, in the informal and stimulating atmosphere of the venue on the Lungomare of Napoli. Although in existence since time immemorial, natural product chemistry and biology are still dynamic and attractive fields of research with a lot of challenges still to be met, goals to be reached, and developments to be made. The main aim of this conference is to highlight advancements, innovations and future perspectives in these areas of research and to create a fruitful environment that promotes international collaborations and cross-fertilization of ideas. Experts and young scientists will have the opportunity to present their research, while industrial representatives will present the latest applications of natural products.

European Molecular Biology Laboratory | EMBL

This course consists of two parts: virtual and onsite. The virtual course takes place 6 – 10 November 2023 and the onsite part takes place 27 November – 1 December 2023.

The virtual course will cover the basics of SAXS/SANS, instrumentation, data collection, modelling techniques and complementary use with other methods. The students are encouraged to sign-up for a self-paced practical tutorial that covers basic and advanced SAXS data processing steps (including quizzes to keep track of successful participation). In addition, students are encouraged to apply to the ‘add on module’ which includes an on-site visit (5 days) in Hamburg to participate either in track 1: X-ray beamline operation or track 2: sample optimisation for SAXS. Students not travelling to Hamburg can sign up for small discussion groups to discuss their SAXS data in more detail.

Biologie,    Molekularbiologie

Leibniz Research Alliance Advanced Materials Safety

The conference „Advanced Materials Safety 2023” focuses on the impact of advanced materials on human health and the environment and appropriate design concepts supporting their safe and sustainable application. The hierarchical structure that characterizes advanced materials consists of micro- and/or nanostructured building blocks. Together with the wide range of possible compositions, this entails a complex risk potential that must be considered over their entire life cycle. The conference is therefore directed at researchers and stakeholders working in the relevant fields. Regulatory issues, safety communication and facilitation by means of research data handling will be highlighted.

Conference organizer;     Tel.: [+49 681 9300 272];     Email: christiane.petzold@leibniz-inm.de

Assembly and disassembly of safe advanced materials, Sustainable Approaches to advanced materials, Impact of advanced materials on human health, Advanced materials for safe therapeutic applications, Advanced materials in the environment,  Predicting effects of advanced materials by computational modeling

Fachgebietübergreifende Veranstaltungen der Chemie,    Fachübergreifende Veranstaltungen für Physiker

Uventia Global

The safety, quality and clinical results of drug substances and drug products may be disrupted by the formation of nitrosamines along with other mutagenic impurities. The comprehensive development and production of innovative medicines now inevitably involves estimating impurity profiles as well as managing and monitoring them. To meet the demands of ever-increasing regulatory standards and avoid expensive recalls, proactive detection of genotoxic contaminants should be adopted at every stage of pharmaceutical development. We plan an online meeting with subject-matter experts to evaluate multiple perspectives on how to handle the concerns of mutagenic impurities. We will cover regulatory-compliant drug impurity profiling practices; helpful hints for adhering to recent ICH M7 and Q3D updates; nitrosamine impurity identification and quantification; risk evaluation of genotoxic impurities; analytical challenges and genotoxicity prediction; establishment of acceptance criteria; and the most recent developments in the analysis of elemental impurities. Save a seat at our webinar to find out about most effective methods for genotoxic and other mutagenic impurity management.

Email: yuliia.terletska@uventia.com

Genotoxic, Impurities, GTIs, Genotoxins, Genotoxicity, Mutagenicity, Genetic, Toxicology, Chemical Toxicology, Analytical Chemistry

American Academy of Forensic Sciences (AAFS)

Each February, the AAFS scientific meeting gathers together approximately 5,000 world-renowned professionals to present the most current information, research, and updates in their fields. More than 900 scientific papers, seminars, workshops, and other special sessions are presented. In addition, approximately 150 exhibitors showcase the cutting-edge technology and services of this ever-changing profession.

Analytische Chemie, Anorganische Chemie,    Forensische Biologie, Rechtsmedizin

American Geophysical Union (AGU)

AbSciCon brings the astrobiology community together every two years to share research, collaborate, and plan for the future. Diversity, interdisciplinary research and engaging topics make AbSciCon the premier conference for astrobiology.

Astronomie, Astrophysik und Kosmologie,    Biologie

American Association for Clinical Chemistry