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Fusion Conferences

The research field of interorganelle contacts is one of the most rapidly growing areas of modern cell biology. It is becoming clear that many, if not all, organelles form membrane contact sites (MCS) with other components of the cell. The term ‘MCS’ broadly describes a physical interaction between two organelles, occurring at specialized subdomains of the given organelle and involved in multiple facets of the biology of the two organelles that are juxtaposed. MCS discovery forced cell biologists to reconsider the way organelles are studied, introducing the concept that heterotypic organelle interaction allows functions that individual organelles would otherwise be unable to perform and forcing them to think in terms of compartmentalized metabolism and signaling.

Fusion Conferences

Neural development continues throughout life in the mammalian brain. This conference will bring together leaders from diverse fields, such as embryonic cortical development, adult neurogenesis, patient-derived stem cell-based 2D and 3B brain organoid disease modelling, direct reprograming and transplantation to discuss recent advances and remaining gaps in the understanding of the cellular and molecular mechanisms regulating neural stem cell activity, neural fate specification and functional significance of circuitries modified by the addition of new neurons in health and diseases.

Neurologie,    Stammzellforschung und -therapie

Fusion Conferences

The conference program covers how RNA and RNA-dependent machineries govern chromatin landscape, gene expression, and genome architecture during development, homeostasis, and in response to cellular stress. This conference prioritises high-throughput and systems biology approaches that convey new mechanistic insights into genome regulation and will also highlight emerging methods/technology that will propel the field forward in the coming years.

Fusion Conferences

In recent years, significant advancements have revolutionized the ability to study distinct biological features at the level of individual cells, resulting in profound implications for biology and medicine. These breakthroughs encompass novel microfluidic techniques, molecular advancements in next-generation sequencing, spatial technologies, and the development of computational platforms capable of analyzing large-scale sequencing data. As a result, we can now profile the genome (through DNA sequencing), transcriptome (using RNA sequencing), and epigenome (via ATAC sequencing and DNA methylation sequencing) at the resolution of single cells. This wealth of information has provided unprecedented insights into the biological composition of various cell types, tissues, and even whole organisms.

Fusion Conferences

The 6th DNA Repair/Replication Structures & Cancer conference on 14-18 February 2024 will focus on molecular structural and mechanistic insights into dynamic complexes acting in DNA repair, replication, and inflammation and their intersections relevant to advanced cancer therapies. This fundamental information will be pivotal for pioneering research on DNA damage responses as well as for the accurate interpretation of cancer clinical data, design of clinical trials, prognosis, etiology and improving the currently low success rate for oncology drug clinical trials. Informative talks and poster sessions along with vibrant discussions will foster productive interactions, collaborations, and insights. In this conference and this area of science basic research is empowering medical advances and clinical data are unveiling basic relationships in ways that are completely changing how research and translation is being done.

Onkologie,    Genomforschung und Bioinformatik