The field of control theory is central to a wide range of aerospace, energy, automotive, and advanced technological systems and is increasingly recognized as fundamental for emerging fields ranging from nanotechnology, the smart grid to cellular regulation. Moreover, in addition to its traditional ubiquity in process regulation for the physical sciences and engineering, control concepts now pervade the biological, computer, and social sciences. This conference will showcase a wide range of topics in control and systems theory. The topics and applications include control of PDEs, computational mathematics for control and optimization, real-time optimization and data assimilation, cooperative control for unmanned autonomous vehicles, dynamic games, cellular and biological regulation, control of hybrid systems, control techniques for financial mathematics, analysis and control of biomedical systems, risk sensitive control, learning for dynamics and control, control for smart systems such as transportation networks, flow control, and quantum control. This conference is a continuation of a series of meetings started in 1989 in San Francisco.