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EMBO Workshop — The 20S proteasome degradation pathway
08. Jan 2023 - 12. Jan 2023 • Rehovot , Israel
Veranstalter:
European Molecular Biology Organization – EMBO
Zusammenfassung:
In the last decade accumulating evidence have demonstrated that the 20S proteasome can function in a free, uncapped form, leading to the processing and degradation of partially unfolded proteins. Various functional roles have been associated with this activity, including neuronal communication, antigenic peptide production, regulation of protein function through post-translational processing and extracellular activities. However, up until now a community effort to advance this field of research or a platform for exchanging knowledge and ideas was lacking. Therefore this meeting will be specifically dedicated to the independent activity and regulation of the 20S proteasome. We believe that such an event will lead to a supportive and collaborative community and advancement of the research. During the meeting, there will be social events and round-table discussions generating a fruitful platform for establishing international ties and novel collaborations.
Einsendeschluss für Abstracts:
15. Okt 2022
Eintrags-ID:
1454207
2
EMBO Workshop — Mechanisms of neuronal remodelling
11. Mär 2023 - 14. Mär 2023 • Kibbuz Nahsholim, Israel
Veranstalter:
European Molecular Biology Organization – EMBO
Zusammenfassung:
Developmental neuronal remodelling is essential for establishing functional nervous systems across species. Remodelling involves specific elimination of existing connections, typically followed by strengthening of surviving synapses or even axon regrowth to develop new, adult-specific connections. While altered remodeling has long been suspected of contributing to neuropsychiatric conditions, such as autism, schizophrenia, and ADHD, studies only recently established firm molecular similarities between such disorders and developmental remodeling. Moreover, the mechanisms involved in developmental remodelling appear to be reiterated in neurodegeneration and during regeneration. Despite these significant advances in the field, many important questions remain open and will be discussed at this meeting.
Einsendeschluss für Abstracts:
01. Okt 2022
Eintrags-ID:
1498391
Verwandte Fachgebiete:


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