Mitochondria act at the interface of numerous processes critical for cellular function and organismal health. Long recognized as the powerhouses of the cell, mitochondria are emerging as hubs for cellular metabolism, redox balance, signalling, gene expression, detoxification, and ion homeostasis. Mitochondrial maintenance is critical for proper development and function of cells and tissues, and mitochondrial dysfunction underlies numerous disease processes ranging from severe childhood mitochondrial disorders, to heart disease, neurodegenerative disorders, cancer, and aging itself. This conference will bring together scientists and clinicians with expertise in a breadth of mitochondrial biology to explore topics at the interface of basic and translational biology. Mitochondrial basic mechanisms of organelle regulation, mitochondrial mechanisms of disease, cutting edge technologies, and interventional strategies will be emphasized in interactive scientific sessions.
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