Conférences  >  Sciences biologiques  >  Biologie moléculaire  >  Royaume-Uni

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1
Genotype to Phenotype: Bridging Comparative Genomics and Cell Biology
13 nov 2022 - 16 nov 2022 • Buxted Park, East Sussex, Royaume-Uni
Organisateur:
The Company of Biologists Ltd
Résumé:
In this Workshop, we aim to bring together computational, cell, and evolutionary biologists to help address this major challenge of integrative cell biology. We strongly believe that actively seeking out collaboration across fields will be crucial to push cell biology beyond the boundaries of individual species into a truly comparative discipline anchored to predictive models. In turn, computational biologists will have an opportunity to guide and influence the next phase of big data generation in cell biology. Together, in deciphering the rules that underpin the relationship between the genome and the cell that encases it, we will better understand both evolution and cellular function.
Identifiant de l'évènement:
1473319
Sujets apparentés:
2
Toxic Metabolites in the Biology of Ageing and Cancer
04 dec 2022 - 07 dec 2022 • Buxted Park, East Sussex, Royaume-Uni
Organisateur:
The Company of Biologists Ltd
Résumé:
This Workshop will focus on the biology of toxic metabolites in the ageing process, stem cells and cancer. Specific emphasis will be placed on how metabolites that carry carbonyls (such as aldehydes and ketones) damage stem and cancer cells. A particular area will focus on endogenous aldehydes (such as acteladehyde, formaldehyde and methyl-gyoxal), the enzymes that remove them [aldehyde dehydrogenases (Aldh) and functionally related glutathione-based enzymes such as Adh5 and Glo-1/2]. Further, we will consider how human genetic variation can contribute to metabolite sensitivity, and how mutations in cancer genomes in toxic metabolism pathways can be exploited for therapy.
Identifiant de l'évènement:
1476566
Sujets apparentés:
3
Workshop — Novel Technologies for Programming Human Cell Fate
26 mar 2023 - 29 mar 2023 • Eastwell Manor, Kent, Royaume-Uni
Organisateur:
The Company of Biologists Ltd
Résumé:
This Workshop unites experts in human cell fate engineering and experts in the manipulation and characterisation of single cells. The goal is to fully understand the molecular steps underlying the transformation of one cellular identity into another. The cross-disciplinary selection of speakers spans the fields of cell fate engineering and emerging technologies to analyse and manipulate cells at single-cell resolution.
Sujets:
Direct lineage reprogramming approaches, Assessment of reprogramming inefficiency and infidelity, Engineering cells with defined identity through new methods, De novo predictions of factors and conditions for target cell type generation
Identifiant de l'évènement:
1495851
Sujets apparentés:


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Dernière mise à jour: 8 juillet 2022