Conferences  >  Medicine & Healthcare  >  Epidemiology & Public Health  >  United States

The 2023 GRS on Multi-Drug Efflux Systems will provide an excellent opportunity to globally bring innovative young scientists to share their ideas, foster relationships for future collaborations, and provide friendly feedback to each other for the advancement in the field of Multi-Drug Efflux Systems for improving global health. Scientists attending this seminar will benefit from engaging in interactive sessions, presenting or listening to oral and poster presentations, networking with leaders in the field, and discovering the next steps in their career development.

Insights into the Structure and Function of Multi-Drug Efflux System for Novel Applications in Global Public Health

Multidrug efflux systems export a wide a variety of substrates from cells and consequently are capable of conferring resistance to a wide range of chemotherapeutic agents. Multidrug resistance caused by active drug efflux is one of the major clinical impediments in anti-cancer chemotherapy and treatment of infectious diseases. Multidrug exporters are ubiquitously expressed in prokaryotic and eukaryotic organisms where they regulate absorption, distribution and excretion of xenobiotics, and protect sanctuary tissues by regulating the drug permeability of the blood-brain, -placenta and -testis barriers. In addition to regulating pharmacokinetics, transporters are also major players in dictating tissue-responses to drugs, from pharmacological efficacy to toxicity.

Targeting the Mechanisms and Regulation of Transporters for Advancing Health During a Pandemic