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The Company of Biologists Ltd

This Workshop will bring together experts from a wide range of disciplines to examine the functioning of the vertebrate gastro-intestinal tract though the lens of integrative physiology. Until recently, the gut was the poor relation to other exchange sites with the environment (lungs, gills, and kidneys) in terms of scientific investigation. Indeed, it received scant attention from most comparative physiologists apart from the routine (but questionable) practice of starving their test animals prior to experimentation “so as to standardize their metabolic physiology”. However, many young researchers entering the field of gastro-intestinal physiology have radically altered the landscape, and many established researchers are now switching their focus to this area. Of particular significance has been the recent explosion of research on the importance of the microbiome for digestive health, not only in humans but in animals in general. The gastro-intestinal field is rapidly expanding, and now is a very appropriate time for the cross-disciplinary fertilization that this workshop will encourage.

Isaac Newton Institute for Mathematical Sciences (INI)

The workshop will explore the use of modern mathematical techniques for the study of problems at the interface between biology and mechanics. It includes the use of machine learning, Baysean methods, and uncertainty quantification for a wide range of problems in biology, physiology, and medicine (biophysics of the cell, brain, the heart, morphogenesis,…)

Molekularbiologie,    Biophysik

Isaac Newton Institute for Mathematical Sciences (INI)

This workshop brings together experimental and theoretical researchers who work on cell mechanics, on three different scales. At the microscopic scale, the cytoskeletal active network shapes the cell and generates active forces. At the mesoscale, the collective motion and mechanics of cells gives rises to tissues such as epithelial cell sheets which have become a premier biophysical model system. In the full biological context of cell and developmental mechanics, such as in model tissue organoids, shapes and function arise through the interplay of this active mechanics with morphogens and signalling. Our workshop will explore these three scales of size and complexity, with a view towards bridging the gaps between communities and developing a true multiscale understanding.

Molekularbiologie,    Biophysik

European Molecular Biology Organization – EMBO

Molekularbiologie,    Mikroskopie

European Molecular Biology Organization – EMBO

Molekularbiologie,    Mikroskopie

Isaac Newton Institute for Mathematical Sciences (INI)