Uncertainty quantification (UQ) is essential for establishing the reliability of predictions made by computational models. Such models are often deterministic, and the UQ discipline has traditionally focused on how to quantify uncertainty in that case. Statistical methods play a major role in that effort, and represent an alternative modeling strategy when less is known about the system of interest. The two approaches are naturally synergistic, and with the emergence of machine learning as a practical tool, it is becoming more important than ever to view the whole UQ ecosystem through a unifying lens. UQ is application-driven and inherently interdisciplinary, relying on a broad range of mathematical and statistical foundations, domain knowledge, and algorithmic and computational tools. UQ24 will bring together mathematicians, statisticians, scientists, engineers, and others interested in the theory, development, and application of UQ methods.