Cours et évènements pour étudiants en mathématiques - Allemagne

Over the past decades it became evident that a RNA transcripts specific amount and localisation are important in order to understand the biological function of its (non-) coding gene. Whereby state-of-the-art in situ hybridisation (ISH) technologies are key to visualise these RNAs in a given tissue or cell. This course aims to highlight three powerful RNA visualisation techniques in histological tissue samples. During this course the participants will learn to validate the cellular localisation of candidate genes from transcriptome studies through conventional ISH and, the more recent cutting-edge, smFISH (Single Molecule Fluorescent ISH) and HCR-ISH (Hybridization Chain Reaction), based RNA ISH hybridisation methods. Additionally, the course will also cover essential tissue embedding protocols that are adapted for use in visually interrogating RNA transcripts in mammalian tissues.

EMBL Events;     Tél.: [+49 6221 378 8797];     Email.: events@embl.de

Biologie,    Biologie moléculaire

Hausdorff Center for Mathematics

Hausdorff Center for Mathematics (hcm)

The Circle Method emerged one hundred years ago from ideas of Ramanujan, Hardy and Littlewood, and quickly became the most powerful analytic method for counting solutions to Diophantine equations. As the Circle Method enters its second century, new work is making significant advances both in strengthening results in classical Diophantine settings, and in demonstrating applications in novel settings. This includes function field, number field, adelic, geometric, and harmonic analytic applications, with striking consequences in areas such as ergodic theory, subconvexity for L -functions, and the Langlands program. This summer school for graduate students and postdocs will present accessible lecture series that demonstrate how to apply the Circle Method in a wide variety of settings.