The symposium will examine how the study of a person’s facial features or expressions as indicatives of character or ethnicity, has evolved from the crossroad of magic, religion, and primitive medicine to present day cultural preoccupation with wellness and beauty. In this context, the discoveries of regional (cranio-facial) neurophysiology and psychology and the practice of cosmetic and reconstructive surgery have a centuries old relationship with physiognomy. As the study of one’s outward appearance evolved from its classical roots and humanistic self-representations through 18th and 19th century adaptations in fiction and travelogues, it gradually became a scientific discipline. Along the way, however, physiognomy came to be associated with the pseudo-sciences of phrenology and craniology and used to promote eugenic policies. Thus, it became tainted with racial bigotry and biological determinism, and trapped within questions of delinquency, monstrosity and posthumanism. In short, throughout its history, physiognomy has played both positive and negative roles in the evolution of significant aspects of the socio-cultural order of the western world that merit contemporary update and in-depth study.