Meetings/Workshops on Biotechnology in the United Kingdom

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1
Molecular Hiving™ Technology — Cost-efficient and Green Manufacturing of Peptides thanks to Molecular Hiving™ Technology
26 Nov 2020 • Online Webinar, United Kingdom
Organizer:
SMi Group
Abstract:
Bachem and Jitsubo CO., Ltd. recently announced the signature of an exclusive Licensing Agreement for Jitsubo’s Molecular Hiving™ Technology. Under the License agreement, Jitsubo will develop selected manufacturing processes using their Molecular Hiving™ Technology and transfer these processes to Bachem. Bachem will further optimize, scale up and produce for commercial applications. Molecular Hiving™ is a tag-assisted liquid-phase peptide synthesis technology developed by Professor Kazuhiro Chiba at Tokyo University of Technology and Agriculture. This technology uses a hydrophobic tag, which is applied in the same way as the resin for solid-phase peptide synthesis (SPPS) processes. The same standard Fmoc amino acid derivatives as for SPPS are applied for assembling the peptide chain. However, all couplings and cleavages of the Fmoc protecting group are performed in solution allowing for fast reactions and direct in-process controls, e.g. by HPLC. Excess reagents as well as coupling and cleavage related by-products are solely removed by aqueous extractions. Therefore, intermediate isolation of the tag-bound peptide and excessive washing steps are not required for Molecular Hiving™ Technology. In this webinar, the speaker will guide you through the individual steps for synthesis of peptides applying Molecular Hiving™ Technology. You will learn about the scalability and the substantial advantages of this technology regarding efficiency and towards greener manufacturing, as solvent consumption and material requirements are significantly reduced compared to conventional SPPS processes. Molecular Hiving™ also allows the synthesis of peptides without the use of solvents and reagents which are carcinogenic, mutagenic, or toxic to reproduction (CMR substances). This makes peptide products manufactured by this technology highly attractive for the pharmaceutical and cosmetics industry.
Contact:
Phone: [02078276000];     Email: ssapal@smi-online.co.uk
Topics:
Drug Development, Peptide Synthesis, Molecule, Drug Discovery, Peptides, RNai,
Event listing ID:
1383378
2
3D Cell Culture — SMi’s 5th Annual 3D Cell Culture Conference
10 Feb 2021 - 11 Feb 2021 • Online, United Kingdom
Organizer:
SMi Group
Abstract:
3D Cell Culture is gaining momentum in the pharmaceutical industry, with the global 3D Cell Culture market predicted to surpass a value of $3.2 Billion by 2027. Researchers globally are realising the potential of in vitro applications for drug discovery, predictivity and validation, safety, and toxicity. SMi’s 5th Annual 3D Cell Culture Conference will be covering the application of 3D cell culture to drug development, toxicity testing, and safety assurance. In addition, the conference will look into the newest breakthroughs in Organ Chip technology, 3D Multicellular scaffolding, Microphysiological Systems, and 3D Bioprinting. In recent years technological advances have made these technologies viable and accessible in scientific application.
Contact:
Phone: [02078276000];     Email: ssapal@smi-online.co.uk
Topics:
Organ-on-chips, microfluidics, cell culture, 3D cell culture, 3D bioprinting, bioprinting, organoid, extracellular matrix, ECM, tissue engineering, physiochemical factors, cell-based assay, cytotoxicity, cell metabolic pathways, cancer research, molecular diagnostics, cell and gene therapy, microphysiological, co-culture systems complex in-vitro models, high throughput screening, 3D imaging, drug screening, extracellular matrix scaffolds, 3D drug development, regenerative therapies
Event listing ID:
1383302


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Last updated: 09 October 2020