Conferences  >  Life Sciences  >  Molecular Biology

This highly dynamic field combines theoretical, computational, biochemical, physical, and cellular approaches to understand the molecular mechanisms that shape life. The 2023 GRS meeting will focus on recent advances in these areas, which have allowed a better understanding of how proteins shape and power biology. Topics will include protein folding, binding interactions, allostery, evolution, design, cellular signaling, macromolecular organization, and more.

Combining Theory and Experiments to Understand Mechanisms of Function

Launched in 2007, this cross-disciplinary FASEB Science Research Conference (SRC) is focused on endoplasmic reticulum (ER) function and dynamics, and the contribution of ER dysfunction to disease.  The conference brings together cell biologists and disease-oriented researchers, including both trainees and independent investigators. It attracts basic researchers interested in protein folding, protein secretion, cellular stress responses, protein post-translational modification, proteasome dependent protein degradation, and regulation of lipid biosynthesis, as well as researchers focusing on a range of pathologies, including diabetes, neurodegeneration, cancer, and diseases of protein misfolding.

European Molecular Biology Organization – EMBO

Protein science is continuing a dramatic renaissance with the emergence of ever-more powerful methods of structural biology, computation, and molecular biology. The arena of practical applications of protein science continues to expand explosively. The 2023 Proteins GRC will highlight “complexity in proteins” by bringing together experimental, theoretical and computational biochemists, biophysicists, chemists, chemical biologists, biologists and bioengineers who study the diverse aspects of protein science including protein function, dynamics, thermodynamics and structure using cutting-edge techniques and strategies.

Complexity in Proteins

Oxford Global Conferences

Gene Therapy Development & Manufacturing 2023 delivers in-depth discussion on optimised process strategies and technologies for the successful technical development and manufacture of advanced gene therapy products.

Phone: [+44 1865 248455];     Email: h.liddiard@oxfordglobal.co.uk

Gene therapy, biology, vector development, gene editing, personalised medicine

European Molecular Biology Organization – EMBO

The aim is to explore with attendees their own approach to leadership – and the approaches of the other participants - and use this insight to define for each individual how they want to lead and manage their research groups or other teams. The course also provides insight into how teams work best together and how to identify and resolve barriers to the efficient operation of teams. Throughout the course, the trainers provide tools, techniques and insight tailored specifically to the laboratory/research setting for the management of teams, good communication, healthy resolution of conflict and the management of workloads and responsibilities.

Biology,    Career, Leadership and Management

The Royal Society of Chemistry

This 2.5 day symposium is the third in the very successful series of biannual meetings started in 2017 containing high quality international speakers from industry and academia on topics of Medicinal Chemistry and related enabling technologies. Organised by the Biological and Medicinal Chemistry Sector of the Royal Society of Chemistry, together with Nordic affiliates, the meeting promises to be an exciting and invigorating gathering packed with fantastic opportunities to disseminate knowledge and expand networks.

European Molecular Biology Organization – EMBO

The discovery of myriad noncoding RNAs (ncRNAs) over the past decade has revealed a universe of new and exciting therapeutic opportunities. Many thousands of microRNAs, piRNAs, circular RNAs, long noncoding RNAs, and others are expressed across healthy and diseased human tissues and play key functional roles in pathogenic states and processes. Their regulatory roles, cell-type-specificity, and vast numbers confer on ncRNAs unique advantages as therapeutic targets. Rapid advances in clinical transcriptomics, oligonucleotide therapeutics, and RNA-directed small molecules, open the possibility for rapid, economical, and personalised ncRNA-directed therapies. Reaching this goal will require overcoming key challenges, including low evolutionary conservation in model species, poorly-characterised molecular mechanisms, finding hits amongst the vast ncRNA transcriptome, and effectively drugging targets in vivo. This EMBO Workshop will bring together colleagues from both academic and commercial worlds to discuss their latest progress in these issues. Sessions will cover the full span from basic disease biology to therapeutic development. Confirmed speakers represent leaders from around the globe, and numerous slots have been set aside for oral presentations selected from submitted abstracts.

European Molecular Biology Organization – EMBO

This EMBO practical course aims to provide a theoretical and practical overview of state-of-the-art techniques for the characterization of various PTMs, such as phosphorylation, acetylation, cysteine PTMs and glycosylation, and their cross-talking in controlling dynamic cellular mechanisms. The laboratory part will focus on a case study of EGF stimulated SILAC labeled HeLa cells. You will be introduced to enrichment, identification and quantitation of the PTM peptides and to mass spectrometry analysis as well as data interpretation and bioinformatics. This will provide you with knowledge needed to perform quantitative large-scale PTMomics from small amounts of sample material yourself. You will be taught in methods developed in the laboratories of the speakers and they will provide you with their own tips and tricks.

European Molecular Biology Organization – EMBO

Biology,    Career, Leadership and Management

Understanding the molecular mechanisms of gene expression regulation and their implications in drug development/medicine will be the general theme of the 2023 Nucleic Acids GRS. The meeting will also serve as a platform to discuss recent technical developments in cutting-edge microscopy and next generation sequencing methods employed by nucleic acid researchers.

Mechanism Meets Medicine

European Molecular Biology Organization – EMBO

Advanced reproductive technologies, such as intracytoplasmic sperm injection, have revolutionized reproductive medicine by enabling effective fertilization without the need to understand the cause of infertility. However, declining male fertility persists in many countries, and growing evidence suggested that the reproductive health of fathers affects their children’s health, calling for continuing investigation of the underlying mechanisms. The main themes of this EMBO Workshop are the male reproductive system, testis development, and sperm formation in mammals, including humans and animal models. Reflecting the multifaceted nature of male reproduction and discoveries made by increasingly advanced experimental techniques, the three broad topics further branch into sub-topics including genetics, epigenetics, immunity, lifestyle influences, toxicity, immunology, and endocrinology. Clinically relevant topics—semen function, sperm physiology, reproductive technologies, and fertility preservation—are also incorporated. This EMBO Workshop aims to bridge the knowledge gap in male reproduction, facilitate networking among research groups with different expertise, and promote the translation of fundamental research in male reproduction into diagnoses and therapies.

European Molecular Biology Organization – EMBO

Meiosis is a defining feature of sexual reproduction. This specialized cell division program comprises a single round of DNA replication followed by two successive cell divisions, thereby reducing chromosome number by half. This reduction accommodates the later combination of two haploid gametes during fertilization to reconstitute a full diploid genome. The unique events of meiosis, including pairwise alignment of parental chromosomes, inter-homolog recombination, kinetochore attachment, cell cycle adaptations and error correction mechanisms, are intensely studied processes in numerous model organisms (fungi, protists, plants, and animals). The Meiosis field is driven by fascination in how evolution has implemented and perfected the meiotic program, and also by its significance to both plant breeding and human health. As a special topic for the 2021 EMBO Workshop, we have chosen homolog pairing. The recognition and physical pairing of homologous chromosomes is an essential feature of meiosis, and also occurs in other contexts. It is therefore timely to bring together the fields of meiotic and post-meiotic chromosome pairing to potentially uncover common principles and mechanisms.

Unraveling the Mechanisms of Membrane Transport: Structure, Dynamics and Allosteric Regulation

European Molecular Biology Organization – EMBO

Biology,    Systems Biology and Computational Biology

The Nucleic Acids Gordon Research Conference (NAGRC) is the premier meeting for exchange of new ideas about the structure and mechanistic behavior of nucleic acids and their cellular processing factors, and the potential applications of innovative developments in RNA and DNA science. Historically, the meeting has provided a powerful forum for synthesizing cutting edge information that leads to ground-breaking discoveries and world-changing technologies. An important feature of the meeting is the inclusion of late-breaking findings and the active participation of early career scientists who are at the forefront of nucleic acid science.

Structural, Functional and Mechanistic Behavior of DNA, RNA and Nucleic Acid Processing Enzymes

European Molecular Biology Organization – EMBO

Since 2009 the Glyco-Bioinformatics Symposium aims at establishing a network of experts in glycochemistry, biology, bioinformatics and computer sciences. In addition, it provides a platform to discuss the latest outcomes presented by the MIRAGE Commission.

Unparalleled diversity and functionality of the glycome

Genomics and Bioinformatics,    Scientific Computing and Data Science

Cambridge Healthtech Institute

The ubiquitin-proteasome, lysosome and autophagy systems are all well-controlled, selective degradation pathways that are key cellular regulators in cancer, CNS, and other diseases. A new generation of hetero bi-functional chimeras and small molecule monovalent degraders are being developed to hijack these systems for targeted protein degradation or stabilization. These molecules that include Proteolysis-targeting chimeras (PROTACs) and molecular glues are being used to seek out previously “undruggable” targets for therapeutic intervention. However, challenges do exist in terms of specificity, stability, biodistribution and penetration of these degrader molecules. This conference on Next-Generation Degraders & Glues brings together experts in the field to discuss these new therapeutic modalities, as well as issues underlying the use of targeted degradation as a new therapeutic approach.

Marketing Manager;     Email: aorktiese@healthtech.com

PROTACs, Molecular Glues, Protein Degradation

European Molecular Biology Organization – EMBO

Postponed from 21.09.2021–24.09.2021

Viruses are major human pathogens that cause a wide range of infectious diseases, representing a constantly recurring challenge to the health of individuals and the functioning of human society. Only a profound understanding of viral biology will provide the basis for developing and improving antiviral therapies. While RNA turnover has long been studied in the context of cellular gene regulation and quality control mechanisms, the interplay between RNA turnover and viral life cycles is only now emerging as a key component of virus-host interactions. For example, Herpes viruses, Poxvirus, Influenza virus and SARS-Coronavirus encode ribonucleases that cleave host mRNA and thereby support virus reproduction. Flaviviruses such as Dengue virus, West Nile virus and Hepatitis C virus encode a non-coding RNA that blocks Xrn1, a major cellular exoribonuclease, as a means to escape from an antiviral activity. The endonuclease RNase L is another component of the mammalian antiviral defense system, highlighting the importance of ribonucleases in the encounter of viruses with their host cells.

This EMBO Workshop will bring together molecular biologists working on basic mechanisms controlling RNA turnover with virologists exploring RNA turnover in the context of virus-host interactions, and propel the scientific exchange in this emerging area of research.

European Molecular Biology Organization – EMBO

Biology,    Career, Leadership and Management

The focus of this meeting is to highlight advances in the field of nucleosides, nucleotides, and oligonucleotides. Speakers will discuss chemical biology, synthesis, structure, and therapeutic applications of natural and engineered small molecules and oligomers.

Chemical Biology and Clinical Applications of Nucleosides, Nucleotides and Oligomers

European Molecular Biology Organization – EMBO

Polyamines in Cancer, Medical Genetics, Aging, Pathogens and Plants

For many years, nucleos(t)ide analogues and nucleic acids have served as cornerstones of drug design and development efforts. The Nucleosides, Nucleotides and Oligonucleotides (NNO) Gordon Research Conference is dedicated to understanding the fundamental chemistry, biology, and technologies for the diagnosis and treatment of various diseases using nucleos(t)ides and nucleic acid analogues. In recent years nucleic acids have seen wide use in chemical biology investigations as well as in the clinic as therapeutics and diagnostics. Emerging areas like CRISPR gene editing and siRNA have been developed due to the extensive efforts of many in the NNO field. The 2023 edition will be the 21st NNO GRC and will reflect the evolution of the field and the current explosive growth of NNO based therapeutics, from its original focus on purine and pyrimidine chemistry and biology, to the much broader current scope.

Chemical Biology of Nucleosides and Nucleic Acids Towards Human Therapeutics

Pharmacology and Drug Development,    Biochemistry and Medicinal Chemistry, Toxicology

Laboratory of Support to Research in Molecular Medicine and Department of Biomedicine, Faculty of Medicine of the University of Porto

The Essential Molecular Biology course covers the fundamental principles and techniques used in experimental research in the area of Molecular Biology.

Essentially practical in nature, it aims at the learning of current genomics and proteomics techniques, as well as the acquisition of skills in laboratory experimentation required for scientific research in Biomedicine.

An exciting way to learn the essential genomics and proteomics techniques used in experimental research in biomedicine: hands-on, practical, intensive.

Phone: [00351 220 426 779];     Email: mlsoares@med.up.pt

Molecular biology, genomics, proteomics, hands-on, laboratory work, practical

European Molecular Biology Organization – EMBO

In this workshop, EMBO Press editors work with PhD students, Postdocs or junior group leaders on the principles and practicalities of peer review. Topics covered include the key elements of good peer review and the role of peer review in publishing reproducible science. We also discuss ethical considerations such as conflicts of interest and give guidelines to young scientists about how to become good reviewers. The course includes a balanced combination of theory presentation, group work, and interactive discussions to keep the participants engaged.

Biology,    Career, Leadership and Management

European Molecular Biology Organization – EMBO

The antibody response and the complement system are major effector arms of the immune system. Next to their beneficial roles in host defense, antibodies and complement are also involved in a plethora of pathological conditions—including autoimmunity, allergy and cancer—and regulate, mainly through their receptors (FcR and CR respectively) cell activation, migration, survival but also metabolism. As the portfolio of antibody—and complement-effector function grow, high-end technological solutions are developed, and novel therapeutic applications are proposed. This EMBO Workshop on Antibody & Complement will be a forum for leaders in the field and new investigators coming from academia, industry and research institutes to discuss where the field is going and what challenges lie ahead. We will focus attention on key advances in both fields with the aim at fostering discussions between antibody experts and complement experts.

European Molecular Biology Organization – EMBO

The successful management of research projects is key to success in science. Understanding what project management is, when it is helpful and how to apply it in research is an important skill for scientists. This course, developed by CJ Fitzsimons—author of "International Project Management - intercultural cooperation in practice" (German language)—introduces key concepts in project management, both for planning and managing work, and for working effectively with people (including with yourself). The course is in English.

Biology,    Career, Leadership and Management

European Molecular Biology Organization – EMBO

Banff International Research Station (BIRS) for Mathematical Innovation and Discovery

Cells are the fundamental building blocks of life. Recent advancement in biotechnology has allowed us to peek inside this every cell for better understanding of biology and human disease. Single-cell technology also generates big and complex data and brings about new data science challenges for computational and life scientists. The objective of this workshop is to bring together international leaders in diverse disciplines including mathematical, statistical, computational, biological and medical in a collaborative atmosphere to develop the collaborative capacity that will tackle various underlying data science challenges in single-cell research.

Systems Biology and Computational Biology,    Scientific Computing and Data Science

Faculty of Biology, Adam Mickiewicz University, Poznan

We are pleased to invite you to participate in the fourteenth edition of the Poznan Summer School of Bioinformatics organized by the Faculty of Biology of Adam Mickiewicz University, Poznan, Poland. The title of this year's edition is "Analysis of single-cell data". The course is suitable for beginners as well as for those with basic knowledge in the field of bioinformatics and will be held in English. The course will be largely hands-on, allowing you to familiarize yourself with the topics discussed and to practice the problems presented.

PSSB Organizing Committee;     Email: genomics@amu.edu.pl

Introduction to R, Introduction to Bioconductor, scRNA-seq Data Analysis, Single Cell Metabolomics, Correlation-based Network Analysis of Metabolites

Genomics and Bioinformatics,    Biotechnology

European Molecular Biology Organization – EMBO

Biology,    Biophysics, Medical Physics

Fusion Conferences

The conference will provide the platform for researchers in the recombination and repair fields to present their new unpublished data that sheds novel insights into not only the mechanisms of DSB repair by recombination, but also the consequences of inaccurate repair leading to cancer. It is now clear that many inheritable cancers, including those linked to defects in the BRCA1 or BRCA2 genes, are caused by defects in homologous recombination. Understanding the precise mechanisms of recombinational repair is therefore critical for the development of new drugs that can target these diseases and improve human health.

Biology,    Genomics and Bioinformatics

UC Santa Barbara, Kavli Institute for Theoretical Physics (KITP)

A long-standing question in the neurobiology of learning is that of timescales. The brain can associate events that are separated by seconds, minutes, hours, days, weeks, or longer. Yet, the known biological mechanisms for inducing changes in the synaptic connections between neurons are driven by neural events that are separated by typically no more than a few tens or hundreds of milliseconds. This conference will convene scientists studying the molecular, cellular, and circuit-level mechanisms used by the brain to bridge the multiple timescales across which events play out in the experience of an individual. The goal will be to assemble an up-to-date understanding of the set of biological mechanisms available in the brain to support associative learning across different timescales. The conference's emphasis on biological mechanisms will complement and support the main program’s more computational focus, and encourage an integrated analysis of statistical learning spanning molecular, cellular, circuit, and behavioral-level phenomena.

Neural Networks and Artificial Intelligence, Machine Learning,    Neurology

European Molecular Biology Laboratory | EMBL

As fluorescence lifetime-based readouts become more accessible, this course aims to provide a broad understanding of how the lifetime-based information can be leveraged to solve biological questions. This application-centred course will provide insights into how this additional dimension of fluorescence information can help unveil functional and mechanistic information.

Biology,    Microscopy

European Molecular Biology Organization – EMBO

In this interactive workshop, trainers work with participants to explore the principles and challenges of integrity and reproducibility in research. Research integrity is addressed at multiple stages of the research process, from experimental design to the analysis and sharing of results.  Participants will gain a better understanding of the ‘dos’ and ‘don’ts’ of conducting and sharing scientific research and will realise that research integrity is important and valuable not only for the scientific record, but also for their own work and careers.

Biology,    Career, Leadership and Management

Fusion Conferences

Mitochondria act at the interface of numerous processes critical for cellular function and organismal health. Long recognized as the powerhouses of the cell, mitochondria are emerging as hubs for cellular metabolism, redox balance, signalling, gene expression, detoxification, and ion homeostasis. Mitochondrial maintenance is critical for proper development and function of cells and tissues, and mitochondrial dysfunction underlies numerous disease processes ranging from severe childhood mitochondrial disorders, to heart disease, neurodegenerative disorders, cancer, and aging itself. This conference will bring together scientists and clinicians with expertise in a breadth of mitochondrial biology to explore topics at the interface of basic and translational biology. Mitochondrial basic mechanisms of organelle regulation, mitochondrial mechanisms of disease, cutting edge technologies, and interventional strategies will be emphasized in interactive scientific sessions.

Biology,    Human Physiology and Metabolism

European Molecular Biology Organization – EMBO

Recent progress in biology has led to an explosion of factual knowledge about the living world over a huge range of scales in space and time. Yet, many questions about how to make sense of this data remain across the entire diversity of the living world from the smallest bacterium to the ecosystems of the Serengeti. This meeting aims to bring together a diverse collection of researchers interested in finding ways to parlay this ever-increasing factual knowledge into a corresponding array of conceptual knowledge. The goal of this symposium is to assemble an interdisciplinary community and to provide a platform to discuss perspectives on the role of theory in biology, and importantly also vice versa, the impact that biology can have on theory.

Biology,    Systems Biology and Computational Biology

European Molecular Biology Organization – EMBO

Biology,    Systems Biology and Computational Biology

European Molecular Biology Organization – EMBO

This GRC will be held in conjunction with the "Wnt Signaling" Gordon Research Seminar (GRS). Those interested in attending both meetings must submit an application for the GRS in addition to an application for the GRC. Refer to the associated GRS program page for more information. Conference Program The session topics for this conference are being developed by the conference chairs. Please check back regularly for updates to this information. Contributors Gordon Research Conferences National Institutes of Health - Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) ImmunoPrecise Antibodies STEMCELL Technologies Inc. PeproTech Inc. Pfizer, Inc. Bio-Techne JW Pharmaceutical Corporation Leap Therapeutics Conference Links Conference History Wnt Signaling (GRS) Contribute Financially to This Conference Conference Fees Similar Conferences Poster Information Poster sessions are an integral part of the our conferences, and offer all conferees an opportunity to discuss their research.

Cell Biology and Signalling

Isaac Newton Institute for Mathematical Sciences (INI)

The workshop will explore the use of modern mathematical techniques for the study of problems at the interface between biology and mechanics. It includes the use of machine learning, Baysean methods, and uncertainty quantification for a wide range of problems in biology, physiology, and medicine (biophysics of the cell, brain, the heart, morphogenesis,…)

Biophysics, Medical Physics,    Biology

European Molecular Biology Organization – EMBO

BPS - The Biophysical Society

A vast number of biologically important enzymes, transporters, and other molecules require the participation or transport of protons. Because the proton is unique in many respects, its properties and reactions are often quite distinct from those of other ions. Our goal is to include a truly international spectrum of speakers and attendees. The invited speakers include chemists, structural biologists, and physiologists whose expertise encompasses a wide range of topics that are all related to the proton. We hope to encourage new understandings on levels from basic science to biomedical applications.

European Molecular Biology Organization – EMBO

Any adequate theory of evolutionary change must cover both the sources and the consequences of phenotypic variation. On the one hand, we must understand the various processes—genetic, metabolic, physiological, developmental, and behavioral—that generate variation. On the other hand, we must understand the sorting processes that lead to the differential survival of different variants. The latter aspect is covered by traditional evolutionary genetics, with its well-developed set of concepts and models. In contrast, there seems to be no overarching theory or unifying framework able to explain the enormous diversity of processes generating variation. These processes are not only dauntingly complex, but also occur at many different levels of organization—from the molecular to the cellular, tissue, organ, organismic, and even supra-organismic levels (ecological or social). We could conclude from this that no theory of the sources of variation is possible, or we could call for a novel, empirically grounded, organismic systems biology that integrates philosophical, mathematical, and experimental approaches to tackle the issue. We will look at this project from a broad theoretical vantage point to assess the future of evolutionary and developmental systems biology.

Biology,    Systems Biology and Computational Biology

European Molecular Biology Organization – EMBO

Following the elucidation of the structure of DNA, it was clear that the iconic double helical structure of DNA would impact and impede the fundamental genomic transactions required for cellular life. Even after 70 years of research, novel roles for DNA topology and topoisomerase action in transcriptional control, chromosome structure, anti-viral responses and genome stability are still being uncovered. We are also still deciphering how many chemotherapeutics target topoisomerases and DNA topology impacted processes. The EMBO workshops on DNA topology and topoisomerases bring together scientists who have only recently discovered the importance of DNA topology in their specialties with long standing researchers in the field. This generates a vibrant interdisciplinary meeting, which highlights and disseminates work involving diverse and rapidly evolving approaches. This workshop highlights studies using techniques as varied as single molecule physics and structural biology, pan-genomic analysis of chromosome structure and chromatin composition and live cell single particle tracking to uncover new findings on the nature of DNA topological transactions and how they impact cellular processes.

Isaac Newton Institute for Mathematical Sciences (INI)

This workshop brings together experimental and theoretical researchers who work on cell mechanics, on three different scales. At the microscopic scale, the cytoskeletal active network shapes the cell and generates active forces. At the mesoscale, the collective motion and mechanics of cells gives rises to tissues such as epithelial cell sheets which have become a premier biophysical model system. In the full biological context of cell and developmental mechanics, such as in model tissue organoids, shapes and function arise through the interplay of this active mechanics with morphogens and signalling. Our workshop will explore these three scales of size and complexity, with a view towards bridging the gaps between communities and developing a true multiscale understanding.

Biophysics, Medical Physics,    Biology

European Molecular Biology Organization – EMBO

Biology,    Microscopy

European Molecular Biology Organization – EMBO

Biology,    Microscopy

European Molecular Biology Laboratory | EMBL

Mechanisms that shape cellular proteomes are critical for life. This conference focuses on the process of protein synthesis, from the molecular and structural understanding of the translational machinery to its regulation, its implications in cell and organismal biology, and its alteration in disease. The regulation of mRNA translation is critical to maintain cell homeostasis and mediates cellular responses to environmental, physiological, and pathological cues. Given the central importance of protein synthesis, it is unsurprising that dysregulation or defects in mRNA translation are widely linked to disease, including cancer, neurological or metabolic disorders, and viral infection. In recent years, technical advances have challenged hitherto established dogmas, uncovered new quality control mechanisms, expanded the breath of translation regulators, enhanced our understanding of the dynamics of translation in living cells, and revealed unexpected interconnections with other cellular processes such as metabolism. Advances on these aspects of mRNA translation will be featured, as well as new insights into translation regulation in physiology and disease.

European Molecular Biology Organization – EMBO

European Molecular Biology Organization – EMBO

Biology,    Microscopy

European Molecular Biology Organization – EMBO

This EMBO Workshop strives to connect disciplines from different fast-moving fields linked to endocytosis, which require a common forum to discuss the latest developments and future directions in an integrated fashion. The final goal is to uncover novel molecular and cellular networks involving endocytosis by providing concrete examples of how collaborations between researchers from different disciplines are currently leading to fundamental discoveries.

Biology,    Biophysics, Medical Physics

European Molecular Biology Organization – EMBO

Postponed from 12 - 17 September 2021

The Beilstein Enzymology Symposia series provide not only a platform for the presentation of the latest findings in mechanistic and systemic enzymology but also for discussing standards for measuring and publication of experimental data such as proposed by the STRENDA Commission.

European Molecular Biology Organization – EMBO

Oxford Global Conferences

Join oligo leaders, experts and distinguished scientists in Europe, delivering breakthrough research, technologies & connecting global pharma, biotech and academia for high-level discussions on the latest innovations within the oligonucleotides chemistry & therapeutics development.

Phone: [+44 1865 248455];     Email: h.liddiard@oxfordglobal.co.uk

Oligonucleotides chemistry, biotechnology, oncology, Genetic disorders, Rare diseases, Infectious diseases, Cardiovascular diseases, Kidney diseases

Oncology,    Biotechnology

Oxford Global Conferences

Learn from key opinion leaders working to deliver RNA therapies for several therapeutic areas including infectious disease and cardiovascular disease. Across two in-depth sessions the latest improvements pushing the industry forward will be addressed: from RNA formulation strategies, design and development through to antisense and oligo-mediated RNA delivery and improvements in extrahepatic delivery approaches.

Phone: [+44 1865 248455];     Email: h.liddiard@oxfordglobal.co.uk

RNA, Nanoparticles, Immunology, mMRA, Oligonucleotides

European Molecular Biology Laboratory | EMBL

This course will provide training in genome editing and cell engineering in mammalian cells and mouse embryos using the highly efficient CRISPR/Cas9 system. Participants will learn design of CRISPR targets using bioinformatics tools, generation of gene knock-outs/knock-ins, and target validation using the most current technologies.

Biotechnology,    Genomics and Bioinformatics

European Molecular Biology Organization – EMBO

This EMBO Workshop will bring together an interdisciplinary and diverse group of scientists discussing recent developments and cutting-edge advances in LD research. The meeting is going to provide a unique platform for exchange between basic and clinical researchers across all career levels with ample opportunity for networking and career development.

European Molecular Biology Organization – EMBO

European Molecular Biology Organization – EMBO

European Molecular Biology Organization – EMBO

European Molecular Biology Organization – EMBO

Genome evolution represents the basis of species adaptation to changing environments and habitats. Recent breakthroughs in sequencing technologies resulted in the acquisition of complete genome information for an increasing number of animal species, propelling the field of evolutionary genomics into a new era of discovery. Yet, our limited capacity to interpret genome variation hinders our understanding on how phenotypical changes drive adaptation. This urges the development of novel strategies to reconcile genomic sequence and function, for which a proper integration of cell-specific gene programs, non-coding regulation and 3D chromatin organization becomes essential. Further, establishing causal relationships between genome mutations and phenotypes still remains a major challenge in the field. Within this context, novel synthetic biology approaches are emerging as a means to understand developmental processes in the context of evolution. The aim of this EMBO workshop is to bring together international scientists with distinct, but complementary expertises on interpreting genome variation, on mechanisms of gene regulation and on in vivo synthetic biology approaches. This allows a comprehensive overview that goes from fundamental principles encoded in genomes to their ultimate biological significance on the formation of living, evolving organisms.

European Molecular Biology Organization – EMBO

Biophysical Society

European Molecular Biology Organization – EMBO

European Molecular Biology Organization – EMBO

The ReSOLUTE-IMI Consortium

The RESOLUTE and REsolution consortia of the Innovative Medicines Initiative of the European Union have been empowering over the last years the scientific community with novel research tools and datasets for transporters of the Solute Carrier (SLC) supergroup. In 2023, both projects are coming to an end, and we would like to finish with a big celebratory and future-looking conference: “Unlocking Transporters for Drug Discovery”. At the event expect to see presented the results and lessons learned by the RESOLUTE and REsolution consortia over the last five years. Furthermore, top international scientists interested in metabolism and its regulation, drug discovery, the function and structure of membrane proteins will be speaking.

RESOLUTE Communications Manager;     Email: contact@re-solute.eu

transporters, solute carriers, SLC, genomics, metabolomics, proteomics, systems biology, data integration, drug discovery, medicine, variants, mutants, structural biology, resources, bio-tools, cell lines, plasmids

Systems Biology and Computational Biology,    Genomics and Bioinformatics

European Molecular Biology Organization – EMBO

European Molecular Biology Organization – EMBO

For decades, studies in cell biology have focused on discovering the functions and dynamics of individual organelles. However, organelles do not exist only as single units, but also as part of entities formed through contacts between two or more distinct organelles. In fact, the recent years of studies on inter-organelle contacts have revealed that complex cellular functions, biochemical processes and signaling pathways are governed at the sites where heterotypic organelles come into contact with each other. This paradigm shift has spurred a new gold rush of research in cell biology that is transforming our understanding of cell physiology, signaling and metabolism in health and disease. This EMBO Workshop on inter-organelle contacts biology, now at its 3rd edition, aims at bringing together the community of scientists in this field to share their work, experience, expertise, and vision.

European Molecular Biology Organization – EMBO

European Molecular Biology Organization – EMBO

The successful management of research projects is key to success in science. Understanding what project management is, when it is helpful and how to apply it in research is an important skill for scientists. This course, developed by CJ Fitzsimons—author of "International Project Management - intercultural cooperation in practice" (German language)—introduces key concepts in project management, both for planning and managing work, and for working effectively with people (including with yourself). The course is in English.

Biology,    Career, Leadership and Management

The molecular processes of life are naturally dynamic in space and time from the atomic to the organismal level. The rapid development of imaging methods across the full scale of biological organisation is revolutionising our ability to visualise the inner workings of macromolecular complexes, organelles, cells, tissues, organs and whole organisms. Being able to see biological processes unfold in real time allows us to understand the mechanisms of life as well as disease.

In situ structural biology, Super-resolved imaging, Probes & biosensors, Organismal imaging, Correlative imaging, Image analysis, Discoveries by bioimaging

Biology,    Microscopy

Fusion Conferences

The germline provides an eternal cellular link between generations and is the source of genetic diversity and evolution of animal populations. In addition, perturbations in the epigenome or genome of a parental germline that arise during development could be underlying causes of many disease states in offspring. In males, sperm are the conduit for transmission of genetic and epigenetic information to the next generation and are formed by the complex process of spermatogenesis, which involves undifferentiated stem cell, differentiating, meiotic, and morphogenesis phases. This workshop will explore recent advances in understanding the biology of these different phases in a variety of animal models as well as how epigenetic and genetic abnormalities may underlie transmission of diseases and fertility disorder in humans. Invited talks and poster sessions that focus on cutting edge findings along with vibrant discussions and debates about controversies in the field will provide a rich intellectual atmosphere that is sure to have an important impact on how the biology of spermatogenesis is investigated for years to come.

Biology,    Stem-cell Research & Therapy

Fusion Conferences

The maintenance of genome integrity is critical for the suppression of several pathological disorders in humans, including cancer, infertility and neurodegeneration. Moreover, the accumulation of unrepaired errors in DNA is commonly cited as a likely cause of tissue and organismal ageing. Destabilization of the genome can occur as a result of several cell intrinsic or extrinsic factors, including errors arising during DNA replication or chromosome segregation, as well as exposure of cells to agents that induce DNA damage. In this conference, we aim to bring together scientists studying DNA replication, DNA repair and chromosome segregation with those interested in how chromosomal instability can influence human pathology. Moreover, we aim to show how high throughput and high content screening methods can be used as a discovery tool both for basic science applications and to identify potential therapeutic modalities.

Biology,    Genomics and Bioinformatics

European Molecular Biology Organization – EMBO

European Molecular Biology Organization – EMBO

Over the past decades it became evident that a RNA transcripts specific amount and localisation are important in order to understand the biological function of its (non-) coding gene. Whereby state-of-the-art in situ hybridisation (ISH) technologies are key to visualise these RNAs in a given tissue or cell. This course aims to highlight three powerful RNA visualisation techniques in histological tissue samples. During this course, the participants will learn to validate the cellular localisation of candidate genes from transcriptome studies through conventional ISH and, the more recent cutting-edge, smFISH (Single Molecule Fluorescent ISH) and HCR-ISH (Hybridization Chain Reaction), based RNA ISH hybridisation methods. Additionally, the course will also cover essential tissue embedding protocols that are adapted for use in visually interrogating RNA transcripts in mammalian tissues.

European Molecular Biology Laboratory | EMBL

This course consists of two parts: virtual and onsite. The virtual course takes place 6 – 10 November 2023 and the onsite part takes place 27 November – 1 December 2023.

The virtual course will cover the basics of SAXS/SANS, instrumentation, data collection, modelling techniques and complementary use with other methods. The students are encouraged to sign-up for a self-paced practical tutorial that covers basic and advanced SAXS data processing steps (including quizzes to keep track of successful participation). In addition, students are encouraged to apply to the ‘add on module’ which includes an on-site visit (5 days) in Hamburg to participate either in track 1: X-ray beamline operation or track 2: sample optimisation for SAXS. Students not travelling to Hamburg can sign up for small discussion groups to discuss their SAXS data in more detail.

Biology,    Biochemistry and Medicinal Chemistry, Toxicology

Society for Muscle Biology

European Molecular Biology Organization – EMBO

European Molecular Biology Organization – EMBO

European Molecular Biology Organization – EMBO

European Molecular Biology Laboratory | EMBL

Flow Cytometry is one of the most powerful single cell analysis methods used throughout the life sciences and medicine. By utilising Flow Cytometry we can identify and quantify specific cell populations from heterogeneous samples, analyse the cell cycle or proliferation state or simply detect the expression of fluorescent reporters. In line with the suggestions from our course in 2019, we will significantly enhance the number of analysis sessions together with our partners from FlowJo. We will cover the theory of Flow Cytometry and corroborate this information intensively with the practical issues of the most frequent assays as part of our practical course curriculum.

Isaac Newton Institute for Mathematical Sciences (INI)

European Molecular Biology Organization – EMBO

European Molecular Biology Organization – EMBO

European Molecular Biology Laboratory | EMBL

European Molecular Biology Organization – EMBO

Uventia Global

The safety, quality and clinical results of drug substances and drug products may be disrupted by the formation of nitrosamines along with other mutagenic impurities. The comprehensive development and production of innovative medicines now inevitably involves estimating impurity profiles as well as managing and monitoring them. To meet the demands of ever-increasing regulatory standards and avoid expensive recalls, proactive detection of genotoxic contaminants should be adopted at every stage of pharmaceutical development. We plan an online meeting with subject-matter experts to evaluate multiple perspectives on how to handle the concerns of mutagenic impurities. We will cover regulatory-compliant drug impurity profiling practices; helpful hints for adhering to recent ICH M7 and Q3D updates; nitrosamine impurity identification and quantification; risk evaluation of genotoxic impurities; analytical challenges and genotoxicity prediction; establishment of acceptance criteria; and the most recent developments in the analysis of elemental impurities. Save a seat at our webinar to find out about most effective methods for genotoxic and other mutagenic impurity management.

Email: yuliia.terletska@uventia.com

Genotoxic, Impurities, GTIs, Genotoxins, Genotoxicity, Mutagenicity, Genetic, Toxicology, Chemical Toxicology, Analytical Chemistry

European Molecular Biology Organization – EMBO

Biology,    Systems Biology and Computational Biology

Banff International Research Station (BIRS) for Mathematical Innovation and Discovery

Courses and Events for Math Students and Early Career Researchers,    Graph Theory and Combinatorics

European Molecular Biology Organization – EMBO

This inaugural EMBO | EMBL Symposium aims to showcase the future of plant biology. Going beyond the limited number of model plants that plant biologists have historically focused on (e.g. Arabidopsis, corn, rice), it is nowadays possible to use comparative approaches to uncover the mechanistic basis and the evolutionary drive for the enormous phenotypic variation among the 400,000 species of plants on Earth.

Max Planck Institute for the Physics of Complex Systems (mpi-pks)

MIAPbP - Munich Institute for Astro-, Particle and BioPhysics an institute of the Excellence Cluster ORIGINS

Likely pathways from the inanimate to the animate world involve a transition that can be thought of as the emergence of information in molecular systems. Before this transition, heteropolymers already exist, but the sequence information of a polymer does not persist beyond the lifetime of the polymer. During the transition, information becomes a separate dynamical entity, which lives and changes over longer timescales than its carrier molecules. This transition does not necessarily require the existence of a full-fledged replication machinery, such as polymerase enzymes that copy informational polymers. Instead, the interplay of simpler reactions can create strong correlations in pools of informational polymers, which can also decouple the timescales of the informational dynamics from those of the polymer dynamics. This interplay is only beginning to be studied, experimentally as well as computationally and theoretically, such that many conceptual and methodological questions are currently open. The central aim of this workshop is to bring together scientists with different backgrounds, in order to attack these questions together.

Courses and Events for Physics Students,    Academic Philosophy

Focuses on the convergence in these rapidly evolving areas, spanning from basic biology to clinical diagnostics and therapeutic applications.

Addresses all aspects of development and applications of biomedical optical technologies for research and clinical applications.

Biophysics, Medical Physics,    Optics and Lasers

Photonics, Optoelectronics and Display Devices,    Biology