Conferences  >  Life Sciences  >  Genomics and Bioinformatics

ecSeq Bioinformatics GmbH

The purpose of the workshop is to introduce the concepts of bioinformatic pipeline development through the context of the open source Workflow Management System (WMS) Nextflow. The participants will be trained in the scripting, configuration and execution of example analysis pipelines based on current industry best-practices, and learn how to share them with other users. Finally, the participants will apply everything they have learned by implementing their own analysis pipelines from the ground up. By the end of the workshop all attendees will be enabled to build their own scalable, reproducible bioinformatic pipelines which can be run locally, on high-performance computing clusters or even in the cloud. The course layout has been adapted to the needs of beginners in the field of computational biology and allows scientists with little or no background in software development to get a first hands-on experience in this new and fast-evolving area of expertise.

Event team;     Email: events@ecseq.com

nextflow, bioinformatics, pipeline development, workflow

European Molecular Biology Organization – EMBO

European Molecular Biology Organization – EMBO

This EMBO Workshop series broadly addresses the molecular mechanisms linked to transactions occuring in the eukaryotic cell nucleus (gene expression, nuclear organization/compartmentalization, chromatin remodelling, RNA processing and trafficking, development, evolution, diseases linked to defective nuclear processes). The latest developments will be covered by an outstanding line-up of speakers, and a broad collection of topics are covered. An emphasis is always given to emerging topics and new technologies, which allows attendees to obtain an integrative and up-to date view of the cell's nucleus biology. The workshop usually gathers cell biologists, biochemists and a growing number of physicists/biophysicists due to the types of novel approaches developped and efforts to model and quantify nuclear transactions, which are currently revolutionizing the field and strongly influencing future research.

European Molecular Biology Organization – EMBO

Postponed from 11–15 Oct, 2021 Contact: Gaëlle Legube

European Molecular Biology Organization – EMBO

Postponed from 5–9 October 2020

EMBO | EMBL

Before the genetic information stored in DNA can be used to direct cell growth and metabolism, it has to be transferred into RNA. Messenger RNAs (mRNAs) that code for proteins and noncoding RNAs are key components in the transmission of genetic information in all life forms – from viruses to complex mammalian organisms. Exciting recent findings now reveal a new layer of information added to RNAs in the form of chemical marks (the epitranscriptome) that play a critical role in gene expression control. Following the great success of the virtual 2020 edition of this long-standing symposium, we are looking forward to returning to an in-person meeting for 2022, bringing together leaders in the RNA field, post-docs and students, with the aim of disseminating and discussing the most recent results. The program will include, among others, sessions on transcription, RNA processing and modification, mRNA export and localisation, mRNA surveillance and decay, translation and the control of mRNA expression by microRNAs.

Email: events@embl.de

Transcription, RNA processing, Export and localisation, mRNA surveillance and decay, Translation and the control of mRNA expression by microRNAs, RNA modifications Non-coding RNAs

ecSeq Bioinformatics GmbH

The purpose of this workshop is to get a deeper understanding in Next-Generation Sequencing (NGS) with a special focus on bioinformatics issues. Advantages and disadvantages of current sequencing technologies and their implications on data analysis will be discovered. You will be trained on understanding NGS data formats and handling potential problems/errors therein. In the course we will use a real-life RNA-seq dataset from the current market leader illumina. All workshop attendees will be enabled to perform important first tasks of NGS data analysis themselves. The course layout has been adapted to the needs of beginners in the field of NGS bioinformatics and allows scientists with no or little background in computer science to get a first hands-on experience in this new and fast evolving research topic.

Event Team;     Email: events@ecseq.com

NGS, RNA-Seq, transcriptomics, genetics

Casa Matemática Oaxaca (CMO)

The Company of Biologists Ltd

In this Workshop, we aim to bring together computational, cell, and evolutionary biologists to help address this major challenge of integrative cell biology. We strongly believe that actively seeking out collaboration across fields will be crucial to push cell biology beyond the boundaries of individual species into a truly comparative discipline anchored to predictive models. In turn, computational biologists will have an opportunity to guide and influence the next phase of big data generation in cell biology. Together, in deciphering the rules that underpin the relationship between the genome and the cell that encases it, we will better understand both evolution and cellular function.

Biology,    Molecular Biology

ecSeq Bioinformatics GmbH

The purpose of this workshop is to get a deeper understanding in Next-Generation Sequencing (NGS) with a special focus on bioinformatics issues. Advantages and disadvantages of current sequencing technologies and their implications on data analysis will be discovered. The participants will be trained on understanding their own NGS data, finding potential problems/errors therein and finally perform their first downstream analysis (variant calling). In the course we will use a real-life NGS dataset from the current market leader illumina. All workshop attendees will be enabled to perform important first tasks of NGS data analysis themselves. The course layout has been adapted to the needs of beginners in the field of NGS bioinformatics and allows scientists with no or little background in computer science to get a first hands-on experience in this new and fast evolving research topic.

Event Team;     Email: events@ecseq.com

NGS, Next-generation sequencing, DNA-Seq, RNA-Seq, bioinformatics, sequencing

The 2023 GRS will focus on major areas pertaining to the design of RNA into rationally designed nanostructures. Sessions will follow the developmental pipeline from computational and structural design to use in applications as diagnostics, therapeutics, and materials. Challenges facing the field, including the cellular delivery of these formulations and the immune stimulation of nucleic acid-based nanostructures, will also be explored. The schedule will include talks on research findings as well as poster presentations to drive discussion on these topics and beyond.

Delivery, Design and Function of RNA Nanostructures

Pharmacogenomics, Personalized Medicine,    Molecular Biology

The 2023 GRC on RNA Nanotechnology will promote scientific exchange and cross-disciplinary collaborations among scientists working in RNA chemistry, biology, biophysics, medicine, engineering and biotechnology. The nine sessions will feature presentations on nucleic acid structure and assembly, RNA modification, synthetic biology, nanostructures, biomaterials, extracellular vesicles, therapeutics, diagnostics, and imaging. Each session will also include short talks selected from abstracts submitted by poster presenters. Ample opportunities for extended discussions will be provided after each presentation and during breaks.

RNA Self-Assembly, Packaging, Imaging and Therapeutics

Pharmacogenomics, Personalized Medicine,    Molecular Biology

Faculty of Medicine of the University of Porto

The Essential Molecular Biology course covers the fundamental principles and techniques used in experimental research in the area of Molecular Biology. Essentially practical in nature, it aims at the learning of current genomics and proteomics techniques, as well as the acquisition of skills in laboratory experimentation required for scientific research in Biomedicine. An exciting way to learn the essential genomics and proteomics techniques used in experimental research in biomedicine: hands-on, practical, intensive.

Miguel Soares;     Phone: [220426779];     Email: mlsoares@med.up.pt

Molecular biology, genomics, proteomics, hands-on, laboratory work, practical

Mechanisms and Consequences of Genome Instability

Biology,    Molecular Biology

The Mitochondria in Health and Disease GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships.

Mitochondria Biology

Biology,    Molecular Biology

Exposures to environmental and endogenous DNA damaging agents produce thousands to over a million DNA lesions and chemical modifications to the genome per cell every day. Perturbations in the cellular pathways that respond to DNA damage are linked to myriad human diseases across nearly every cell and organ type. Conversely, dysfunction in DNA damage responses presents new vulnerabilities that are being leveraged to selectively target tumors in a more efficacious and less toxic manner. This GRC will bring together researchers at all levels including principal investigators, lead scientists, postdoctoral fellows and graduate students from academia, government and industry, to share and discuss the latest cutting-edge research on mechanisms of genome maintenance and roles in human health.

Genome Maintenance: From Molecules and Mechanisms to Humans and Therapies

Biology,    Molecular Biology

Fusion Conferences

Understanding processes involving DNA and RNA at the molecular and chemical level is the central theme of this conference, with a marked structural and mechanistic perspective. Every two years we have a hot topic theme and have previously covered ribosome, spliceosome, exosome, ncRNA regulation, DNA replication initiation, DNA topology and repair at past meetings.

Biology,    Molecular Biology

The focus of this year’s meeting is the opportunities and challenges in working with high-throughput phenotyping data. High-throughput phenotyping data encompasses, but is not limited to: omics, sensor and imaging data, electronic health records, activity monitoring, and sequencing. We will discuss the insights we gain into genetics of complex traits using diverse datasets, the challenges we need to overcome, and the opportunities for future research. Statistical, computational, and experimental methods, as well as results stemming from their application, will be presented.

Opportunities and Challenges in Using High-Throughput Phenotyping in Quantitative Genetics and Genomics

The Quantitative Genetics and Genomics GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.

Leveraging High-Throughput Phenotyping Techniques to Study Complex Traits

Studies of the fundamental process of translating mRNA into a protein sequence have greatly advanced our understanding of underlying molecular mechanisms and in consequence their regulation and disease association. Research on mRNA translation involves a wide spectrum of methods from single molecule measurements to the phenotypical characterization of organisms. This GRS will provide a platform where young scientists investigating different aspects of protein synthesis can meet for discussions about experimental approaches, exchange ideas and start collaborations, as well as obtain advice on possible career paths.

Exploring Protein Synthesis from Molecule to Organism

The well-studied process of mRNA translation is fundamental to all biology, and the relevance of this process to disease is emerging rapidly. The 2023 Gordon Research Conference (GRC) on Translational Machinery in Health and Disease will provide a unique forum for both new and established investigators to discuss their latest findings on the relationship of protein synthesis to disease. This interdisciplinary conference will cover connections between translation and a broad range of diseases including cancer, neurological, metabolic, inflammatory, infectious, and mitochondrial disorders. Scientific sessions will highlight recent discoveries on the genetic and molecular disturbances of translation that underlie pathophysiology. Other talks will focus on new technologies to study translation, translation during stress, in pathogens, and in the microbiome. A major goal of this conference will be to foster interactions among scientists at all levels to stimulate data exchange and collaborations across disciplines. Ample time will be provided for formal discussions during the scientific sessions and time will also be set aside for informal discussions. Poster presentations as well as the selection of speakers from submitted abstracts will ensure participation from investigators at all stages of their career. In addition, this GRC will be preceded by a Gordon Research Seminar (GRS) on Translational Machinery in Health and Disease which will be open only to students and postdoctoral fellows. The GRS will complement the GRC and provide a forum for trainees from around the world to broaden their peer network and to explore new directions in translation research.

Protein Synthesis and Cellular Synergy

Mathematisches Forschungsinstitut Oberwolfach (MFO, Oberwolfach Research Institute for Mathematics)

The sixth workshop on this theme has a primary focus on mathematical and statistical methods for analysing genomic data in the context of infectious disease transmission dynamics. A secondary focus area is the development and application of network theory for epidemiology.

Complex Networks,    Applied Mathematics (in general)

The focus of the 2023 GRS is epitranscriptomics, RNA and DNA editing and modifications. These modifications are highly abundant and naturally occurring in nearly all organisms. The GRS on RNA editing brings together graduate student and post-docs to discuss fundamental mechanisms of these modifications and their aberrations in health and disease. The GRS will have two poster sessions and oral talks will be selected from submitted abstracts. The synergistic arrangement of the GRS and GRC will provide multiple opportunities for trainees to build professional networks and foster scientific collaborations.

Diverse Roles of Nucleic Acid Modifications: Biological and Technological Advances in Health and Disease

Molecular Biology,    Biotechnology

The 2023 meeting is subtitled: “RNA/DNA editing and epitranscriptomics across biological systems”. Modifications to the common nucleosides found in DNA and RNA have been known for many years. However, recent advances in analytical techniques for their detection, along with a deeper understanding of the broad impact these modifications have on fundamental biological processes, including human disease, have caused a renaissance in their study. Indeed, we now know that nucleic acid modifications are common in various naturally occurring nucleic acids and influence gene expression, protein synthesis, cognition, innate and adaptive immunity, autoimmune disease and cancer. This meeting will bring together a diverse group of scientists with varying expertise with the common goal of sharing ideas and approaches that can advance our understanding of the many facets of nucleic acid modifications.

RNA and DNA Editing and Epitranscriptomics Across Biological Systems

Molecular Biology,    Biotechnology

CIRM – Centre International de Rencontres Mathématiques

Neural Networks and Artificial Intelligence, Machine Learning,    Modeling and Simulation

European Molecular Biology Organization – EMBO

Regulation of translation is key in the control of gene expression, playing a critical role in many biological and pathophysiological settings. In the last decade, methodological advances have provided comprehensive insights into cellular transcriptomes and proteomes, however, the systems-wide analysis of translation remained an unsolved experimental challenge. The advent of ‘ribosome-profiling’ provided the methodological basis for comprehensive transcriptome-wide analyses of translation at sub-codon resolution by the precise and high-throughput determination of ribosomal positions on mRNA. Its application in a variety of organisms yielded novel insights into protein synthesis and its dynamic regulation, significantly advancing our understanding of the post-transcriptional regulation of gene expression.

European Molecular Biology Organization – EMBO

Fusion Conferences

Epigenetic mechanisms - including DNA and histone modifications, as well as regulation by non-coding RNAs - have pivotal roles in the nervous system. Aberrant epigenetic regulation also contributes to pathogenesis in various brain disorders. There are a number of recent ground-breaking discoveries of new features of epigenetic marks and regulation that are enriched in the nervous system, leading to an emerging new field of “neuroepigenetics”. In addition, new discoveries of modification of mRNAs and long non-coding RNAs lead to a new field of “epitranscriptomics”. This meeting will bring together experts and pioneers in studying neuroepigenetics and epitranscriptomics to provide an up-to-date and comprehensive picture of epigenetic and epitranscriptomic mechanisms in neural development, reprogramming and cell identity, plasticity, neuronal function and dysfunction. The meeting will offer opportunity for interdisciplinary interactions and future collaborations.

Molecular Biology,    Biotechnology

Fusion Conferences

While alterations to DNA underlie genome evolution and antibody diversification, genome instability drives many disorders, including cancer, developmental abnormalities, and neurodegeneration. DNA damage and other genome-threatening replication blocks are generally overcome by a number of DNA repair pathways. The choice of DNA repair pathways, specifically the reliance on error-prone vs. error-free is both intriguing and confounding. Moreover, the deregulation of repair pathway choice can trigger pathological processes. In this conference, we will discuss the delicate equilibrium of genome maintenance pathways, addressing how natural processes such as replication and transcription can threaten genome stability, how the genome can be altered in cancer, signatures of genome instability in human disease, and how cells control the inherent plasticity of their replication and repair machinery. We aim to bring together scientists from diverse fields who are interested in understanding the many processes impacting DNA metabolism and the molecular and biophysical principles that maintain the balance between genome stability and plasticity.

European Molecular Biology Organization – EMBO

Molecular Biology,    Systems Biology and Computational Biology

Fusion Conferences

The conference will provide the platform for researchers in the recombination and repair fields to present their new unpublished data that sheds novel insights into not only the mechanisms of DSB repair by recombination, but also the consequences of inaccurate repair leading to cancer. It is now clear that many inheritable cancers, including those linked to defects in the BRCA1 or BRCA2 genes, are caused by defects in homologous recombination. Understanding the precise mechanisms of recombinational repair is therefore critical for the development of new drugs that can target these diseases and improve human health.

Biology,    Molecular Biology

European Molecular Biology Organization – EMBO

European Molecular Biology Organization – EMBO

This sixth PGE meeting will present a unique opportunity to meet and discuss with colleagues, get updated on the newest developments and insights in plant genome evolution, and will provide unique possibilities to network and discuss collaborations.

Domestication and Evolution of Crops; Decisive Moments and Inventions during Plant Genome Evolution; Polyploidy and Hybridization; Plant Genome Integrity; Climate Adaptation

Botany,    Agronomy, Food Production and Food Chemistry

Fusion Conferences

The maintenance of genome integrity is critical for the suppression of several pathological disorders in humans, including cancer, infertility and neurodegeneration. Moreover, the accumulation of unrepaired errors in DNA is commonly cited as a likely cause of tissue and organismal ageing. Destabilization of the genome can occur as a result of several cell intrinsic or extrinsic factors, including errors arising during DNA replication or chromosome segregation, as well as exposure of cells to agents that induce DNA damage. In this conference, we aim to bring together scientists studying DNA replication, DNA repair and chromosome segregation with those interested in how chromosomal instability can influence human pathology. Moreover, we aim to show how high throughput and high content screening methods can be used as a discovery tool both for basic science applications and to identify potential therapeutic modalities.

Biology,    Molecular Biology