Conferences  >  Life Sciences  >  Genomics and Bioinformatics

Faculty of Medicine of the University of Porto

The Essential Molecular Biology course covers the fundamental principles and techniques used in experimental research in the area of Molecular Biology. Essentially practical in nature, it aims at the learning of current genomics and proteomics techniques, as well as the acquisition of skills in laboratory experimentation required for scientific research in Biomedicine. An exciting way to learn the essential genomics and proteomics techniques used in experimental research in biomedicine: hands-on, practical, intensive.

Miguel Soares;     Phone: [220426779];     Email: mlsoares@med.up.pt

Molecular biology, genomics, proteomics, hands-on, laboratory work, practical

Mechanisms and Consequences of Genome Instability

Biology,    Molecular Biology

The Mitochondria in Health and Disease GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships.

Mitochondria Biology

Biology,    Molecular Biology

Exposures to environmental and endogenous DNA damaging agents produce thousands to over a million DNA lesions and chemical modifications to the genome per cell every day. Perturbations in the cellular pathways that respond to DNA damage are linked to myriad human diseases across nearly every cell and organ type. Conversely, dysfunction in DNA damage responses presents new vulnerabilities that are being leveraged to selectively target tumors in a more efficacious and less toxic manner. This GRC will bring together researchers at all levels including principal investigators, lead scientists, postdoctoral fellows and graduate students from academia, government and industry, to share and discuss the latest cutting-edge research on mechanisms of genome maintenance and roles in human health.

Genome Maintenance: From Molecules and Mechanisms to Humans and Therapies

Biology,    Molecular Biology

Fusion Conferences

Understanding processes involving DNA and RNA at the molecular and chemical level is the central theme of this conference, with a marked structural and mechanistic perspective. Every two years we have a hot topic theme and have previously covered ribosome, spliceosome, exosome, ncRNA regulation, DNA replication initiation, DNA topology and repair at past meetings.

Biology,    Molecular Biology

The focus of this year’s meeting is the opportunities and challenges in working with high-throughput phenotyping data. High-throughput phenotyping data encompasses, but is not limited to: omics, sensor and imaging data, electronic health records, activity monitoring, and sequencing. We will discuss the insights we gain into genetics of complex traits using diverse datasets, the challenges we need to overcome, and the opportunities for future research. Statistical, computational, and experimental methods, as well as results stemming from their application, will be presented.

Opportunities and Challenges in Using High-Throughput Phenotyping in Quantitative Genetics and Genomics

The Quantitative Genetics and Genomics GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.

Leveraging High-Throughput Phenotyping Techniques to Study Complex Traits

Studies of the fundamental process of translating mRNA into a protein sequence have greatly advanced our understanding of underlying molecular mechanisms and in consequence their regulation and disease association. Research on mRNA translation involves a wide spectrum of methods from single molecule measurements to the phenotypical characterization of organisms. This GRS will provide a platform where young scientists investigating different aspects of protein synthesis can meet for discussions about experimental approaches, exchange ideas and start collaborations, as well as obtain advice on possible career paths.

Exploring Protein Synthesis from Molecule to Organism

The well-studied process of mRNA translation is fundamental to all biology, and the relevance of this process to disease is emerging rapidly. The 2023 Gordon Research Conference (GRC) on Translational Machinery in Health and Disease will provide a unique forum for both new and established investigators to discuss their latest findings on the relationship of protein synthesis to disease. This interdisciplinary conference will cover connections between translation and a broad range of diseases including cancer, neurological, metabolic, inflammatory, infectious, and mitochondrial disorders. Scientific sessions will highlight recent discoveries on the genetic and molecular disturbances of translation that underlie pathophysiology. Other talks will focus on new technologies to study translation, translation during stress, in pathogens, and in the microbiome. A major goal of this conference will be to foster interactions among scientists at all levels to stimulate data exchange and collaborations across disciplines. Ample time will be provided for formal discussions during the scientific sessions and time will also be set aside for informal discussions. Poster presentations as well as the selection of speakers from submitted abstracts will ensure participation from investigators at all stages of their career. In addition, this GRC will be preceded by a Gordon Research Seminar (GRS) on Translational Machinery in Health and Disease which will be open only to students and postdoctoral fellows. The GRS will complement the GRC and provide a forum for trainees from around the world to broaden their peer network and to explore new directions in translation research.

Protein Synthesis and Cellular Synergy

Mathematisches Forschungsinstitut Oberwolfach (MFO, Oberwolfach Research Institute for Mathematics)

The sixth workshop on this theme has a primary focus on mathematical and statistical methods for analysing genomic data in the context of infectious disease transmission dynamics. A secondary focus area is the development and application of network theory for epidemiology.

Complex Networks,    Applied Mathematics (in general)

Oxford Global

Oxford Global is proud to present Biomarkers 2023, uniting senior-level experts to provide a focussed forum for thought-provoking discussion and to gain insights from the key figures in the community. The comprehensive programme allows you to gain a forward-looking perspective on the latest technologies and strategies impacting biomarker research across multiple applications and therapeutic areas.

Email: b.westmore@oxfordglobal.co.uk

biomarkers, translational medicine, clinical development, diagnostics, immuno-oncology, neuroscience, cardiology, cell therapies, gene therapies, digital pathology, multi plexing, mass spectrometry, spatial biology

An International conference on Fungal genetics, biology, host pathogen interaction & evolutionary ecology.

Biology,    Molecular Biology

European Molecular Biology Organization – EMBO

Participants will learn fundamental concepts and advanced approaches to reconstruct the demographic history of populations and infer natural selection, using both classic and machine learning-based techniques. Participants will also learn the essential and advanced programming skills required to run the analyses related to the concept presented, with a special focus on machine learning.

The focus of the 2023 GRS is epitranscriptomics, RNA and DNA editing and modifications. These modifications are highly abundant and naturally occurring in nearly all organisms. The GRS on RNA editing brings together graduate student and post-docs to discuss fundamental mechanisms of these modifications and their aberrations in health and disease. The GRS will have two poster sessions and oral talks will be selected from submitted abstracts. The synergistic arrangement of the GRS and GRC will provide multiple opportunities for trainees to build professional networks and foster scientific collaborations.

Diverse Roles of Nucleic Acid Modifications: Biological and Technological Advances in Health and Disease

Molecular Biology,    Biotechnology

The 2023 meeting is subtitled: “RNA/DNA editing and epitranscriptomics across biological systems”. Modifications to the common nucleosides found in DNA and RNA have been known for many years. However, recent advances in analytical techniques for their detection, along with a deeper understanding of the broad impact these modifications have on fundamental biological processes, including human disease, have caused a renaissance in their study. Indeed, we now know that nucleic acid modifications are common in various naturally occurring nucleic acids and influence gene expression, protein synthesis, cognition, innate and adaptive immunity, autoimmune disease and cancer. This meeting will bring together a diverse group of scientists with varying expertise with the common goal of sharing ideas and approaches that can advance our understanding of the many facets of nucleic acid modifications.

RNA and DNA Editing and Epitranscriptomics Across Biological Systems

Molecular Biology,    Biotechnology

CIRM – Centre International de Rencontres Mathématiques

Neural Networks and Artificial Intelligence, Machine Learning,    Modeling and Simulation

European Molecular Biology Organization – EMBO

Regulation of translation is key in the control of gene expression, playing a critical role in many biological and pathophysiological settings. In the last decade, methodological advances have provided comprehensive insights into cellular transcriptomes and proteomes, however, the systems-wide analysis of translation remained an unsolved experimental challenge. The advent of ‘ribosome-profiling’ provided the methodological basis for comprehensive transcriptome-wide analyses of translation at sub-codon resolution by the precise and high-throughput determination of ribosomal positions on mRNA. Its application in a variety of organisms yielded novel insights into protein synthesis and its dynamic regulation, significantly advancing our understanding of the post-transcriptional regulation of gene expression.

VIB

Next generation sequencing has been and is still revolutionizing discoveries across life sciences. While established sequencing technologies are now fully embedded in the clinic and diagnostic settings, novel technological advancements spur the next revolution in sequencing technologies. These will open new avenues for research and enable new genomics insights not possible before. This conference aims to bring together experts in both established and novel sequencing technologies along with top scientists in the field. Over the past decade, technological advances that enable the characterization of single cells at the molecular level rather than in bulk tissues have led to significant breakthrough discoveries with revolutionary insights in diseases, such as cancer, inflammatory and neurodegenerative diseases. Therefore, specific focus of this conference will be on advances in single cell sequencing, ranging from transcriptomics, genomics, proteomics to combined multi-omics analysis at the single cell level. On top, with spatial context of cells becoming increasingly important to unravel cell functioning and behavior, a dedicated session will focus on technological advancements in spatial sequencing and breakthrough scientific discoveries that these have enabled.

This exciting conference puts together an excellent program including renowned leaders in the field that will cover the following topics: Emerging sequencing platforms, New applications of long read sequencing technologies, Computational genomics & data analysis, Outbreak sequencing & population-scale, Single cell sequencing, and Spatial technologies. In addition to a great scientific and technology program, the conference will provide many opportunities to network during the breaks, poster sessions and much more!

Bioinformatics, Computational biology, Epigenomics, Genomics, Machine learning/Artificial Intelligence, Multi-omics, Next-generation sequencing, Sequencing technologies, Single cell technology, Tools & technologies

European Molecular Biology Organization – EMBO

This symposium explores the many ways by which the genome is regulated in the brain in order to support neural function and plasticity. The extraordinary complexity of the brain places unique demands on the genome: How are several hundreds of different neural types specified by the same genetic instructions? Does the genome provide information that guides their connectivity? How is neural activity regulated by and how does it affect genome output? We will explore these fundamental questions from the standpoint of transcriptional regulation and chromatin-based processes, including but not limited to histone marks and variants, chromatin topology and folding, coding and noncoding RNAs, transposable elements, and DNA modifications. The conference aims to bring together neuroscientists and experts in genome regulation. It will cover a broad range of experimental approaches and model systems, from biochemistry to single-cell genomics, from worms to human organoids. Overall, the conference will address the impact of genome regulation on unique features of the brain — its excitable nature, exquisite response to the environment and parallel processing capacity — with the longer-term vision of understanding how defective genome regulation can give rise to brain disease.

Interplay between gene regulation and neuronal activity, Genomic regulation of brain plasticity and behaviour, Chromatin variations in the brain, From one genome to many neurons: neurodevelopment and neural diversity

Molecular Biology,    Neurology

Fusion Conferences

Epigenetic mechanisms - including DNA and histone modifications, as well as regulation by non-coding RNAs - have pivotal roles in the nervous system. Aberrant epigenetic regulation also contributes to pathogenesis in various brain disorders. There are a number of recent ground-breaking discoveries of new features of epigenetic marks and regulation that are enriched in the nervous system, leading to an emerging new field of “neuroepigenetics”. In addition, new discoveries of modification of mRNAs and long non-coding RNAs lead to a new field of “epitranscriptomics”. This meeting will bring together experts and pioneers in studying neuroepigenetics and epitranscriptomics to provide an up-to-date and comprehensive picture of epigenetic and epitranscriptomic mechanisms in neural development, reprogramming and cell identity, plasticity, neuronal function and dysfunction. The meeting will offer opportunity for interdisciplinary interactions and future collaborations.

Molecular Biology,    Biotechnology

Fusion Conferences

While alterations to DNA underlie genome evolution and antibody diversification, genome instability drives many disorders, including cancer, developmental abnormalities, and neurodegeneration. DNA damage and other genome-threatening replication blocks are generally overcome by a number of DNA repair pathways. The choice of DNA repair pathways, specifically the reliance on error-prone vs. error-free is both intriguing and confounding. Moreover, the deregulation of repair pathway choice can trigger pathological processes. In this conference, we will discuss the delicate equilibrium of genome maintenance pathways, addressing how natural processes such as replication and transcription can threaten genome stability, how the genome can be altered in cancer, signatures of genome instability in human disease, and how cells control the inherent plasticity of their replication and repair machinery. We aim to bring together scientists from diverse fields who are interested in understanding the many processes impacting DNA metabolism and the molecular and biophysical principles that maintain the balance between genome stability and plasticity.

European Molecular Biology Organization – EMBO

Molecular Biology,    Systems Biology and Computational Biology

Biomath 2023 is devoted to recent research in life sciences based on applications of mathematics as well as mathematics applied to or motivated by biological studies. It is a multidisciplinary meeting forum for researchers who develop and apply mathematical and computational tools to the study of phenomena in the broad fields of biology, ecology, medicine, biophysics, biochemistry, pharmacokinetics, chemoinformatics, biotechnology, bioengineering, environmental science, etc.

Applied Mathematics (in general),    Systems Biology and Computational Biology

Since 2009 the Glyco-Bioinformatics Symposium aims at establishing a network of experts in glycochemistry, biology, bioinformatics and computer sciences. In addition, it provides a platform to discuss the latest outcomes presented by the MIRAGE Commission.

Unparalleled diversity and functionality of the glycome

Molecular Biology,    Scientific Computing and Data Science

Fusion Conferences

The conference will provide the platform for researchers in the recombination and repair fields to present their new unpublished data that sheds novel insights into not only the mechanisms of DSB repair by recombination, but also the consequences of inaccurate repair leading to cancer. It is now clear that many inheritable cancers, including those linked to defects in the BRCA1 or BRCA2 genes, are caused by defects in homologous recombination. Understanding the precise mechanisms of recombinational repair is therefore critical for the development of new drugs that can target these diseases and improve human health.

Biology,    Molecular Biology

European Molecular Biology Organization – EMBO

European Molecular Biology Organization – EMBO

Following the elucidation of the structure of DNA, it was clear that the iconic double helical structure of DNA would impact and impede the fundamental genomic transactions required for cellular life. Even after 70 years of research, novel roles for DNA topology and topoisomerase action in transcriptional control, chromosome structure, anti-viral responses and genome stability are still being uncovered. We are also still deciphering how many chemotherapeutics target topoisomerases and DNA topology impacted processes. The EMBO workshops on DNA topology and topoisomerases bring together scientists who have only recently discovered the importance of DNA topology in their specialties with long standing researchers in the field. This generates a vibrant interdisciplinary meeting, which highlights and disseminates work involving diverse and rapidly evolving approaches. This workshop highlights studies using techniques as varied as single molecule physics and structural biology, pan-genomic analysis of chromosome structure and chromatin composition and live cell single particle tracking to uncover new findings on the nature of DNA topological transactions and how they impact cellular processes.

European Molecular Biology Organization – EMBO

European Molecular Biology Laboratory | EMBL

This course will provide training in genome editing and cell engineering in mammalian cells and mouse embryos using the highly efficient CRISPR/Cas9 system. Participants will learn design of CRISPR targets using bioinformatics tools, generation of gene knock-outs/knock-ins, and target validation using the most current technologies.

Molecular Biology,    Biotechnology

European Molecular Biology Organization – EMBO

Genome evolution represents the basis of species adaptation to changing environments and habitats. Recent breakthroughs in sequencing technologies resulted in the acquisition of complete genome information for an increasing number of animal species, propelling the field of evolutionary genomics into a new era of discovery. Yet, our limited capacity to interpret genome variation hinders our understanding on how phenotypical changes drive adaptation. This urges the development of novel strategies to reconcile genomic sequence and function, for which a proper integration of cell-specific gene programs, non-coding regulation and 3D chromatin organization becomes essential. Further, establishing causal relationships between genome mutations and phenotypes still remains a major challenge in the field. Within this context, novel synthetic biology approaches are emerging as a means to understand developmental processes in the context of evolution. The aim of this EMBO workshop is to bring together international scientists with distinct, but complementary expertises on interpreting genome variation, on mechanisms of gene regulation and on in vivo synthetic biology approaches. This allows a comprehensive overview that goes from fundamental principles encoded in genomes to their ultimate biological significance on the formation of living, evolving organisms.

This sixth PGE meeting will present a unique opportunity to meet and discuss with colleagues, get updated on the newest developments and insights in plant genome evolution, and will provide unique possibilities to network and discuss collaborations.

Domestication and Evolution of Crops; Decisive Moments and Inventions during Plant Genome Evolution; Polyploidy and Hybridization; Plant Genome Integrity; Climate Adaptation

Botany,    Agronomy, Food Production and Food Chemistry

The ReSOLUTE-IMI Consortium

The RESOLUTE and REsolution consortia of the Innovative Medicines Initiative of the European Union have been empowering over the last years the scientific community with novel research tools and datasets for transporters of the Solute Carrier (SLC) supergroup. In 2023, both projects are coming to an end, and we would like to finish with a big celebratory and future-looking conference: “Unlocking Transporters for Drug Discovery”. At the event expect to see presented the results and lessons learned by the RESOLUTE and REsolution consortia over the last five years. Furthermore, top international scientists interested in metabolism and its regulation, drug discovery, the function and structure of membrane proteins will be speaking.

RESOLUTE Communications Manager;     Email: contact@re-solute.eu

transporters, solute carriers, SLC, genomics, metabolomics, proteomics, systems biology, data integration, drug discovery, medicine, variants, mutants, structural biology, resources, bio-tools, cell lines, plasmids

Molecular Biology,    Systems Biology and Computational Biology

Fusion Conferences

The maintenance of genome integrity is critical for the suppression of several pathological disorders in humans, including cancer, infertility and neurodegeneration. Moreover, the accumulation of unrepaired errors in DNA is commonly cited as a likely cause of tissue and organismal ageing. Destabilization of the genome can occur as a result of several cell intrinsic or extrinsic factors, including errors arising during DNA replication or chromosome segregation, as well as exposure of cells to agents that induce DNA damage. In this conference, we aim to bring together scientists studying DNA replication, DNA repair and chromosome segregation with those interested in how chromosomal instability can influence human pathology. Moreover, we aim to show how high throughput and high content screening methods can be used as a discovery tool both for basic science applications and to identify potential therapeutic modalities.

Biology,    Molecular Biology

European Molecular Biology Laboratory | EMBL