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Isaac Newton Institute for Mathematical Sciences (INI)

This workshop will bring together researchers from biophysics/mechanobiology experiment, soft active matter theory and non-equilibrium statistical mechanics. There will be a mixture of pedagogical overview talks and research talks. The meeting aims to bring together mathematicians and statistical physicists specializing in the fundamental properties of fluctuations and response in nonequilibrium states with theoretical researchers in soft matter working on active matter and biological physics and experimental researchers in biology and biophysics. We expect to enable new collaborations and cross-fertilization of ideas. In short, we expect that understanding the living world will provide challenges that will stimulate new fundamental thinking in statistical physics while current research in this field will help to structure our ever-expanding knowledge of living matter as a nonequilibrium dynamical system.

BPS - The Biophysical Society

An emerging generation of computational models and modeling approaches that cross multiple temporal and spatial scales is enabling new understanding of the mechanisms that regulate striated muscle contraction. These models and their technical underpinnings rely on new, higher-order information about protein and sarcomere structural dynamics, and this is supported by the current resolution-revolution in structural biology. Coupling experimental and computational approaches provides a powerful approach to describe the functional properties and interactions of sarcomere proteins both at rest and during contraction. This understanding then offers new insights into mechanisms that regulate cardiac and skeletal muscle contractile function and its dysfunction in diseases. Moreover, such approaches support the identification of small molecule targets for therapeutic interventions and can predict their mechanism of action. The thematic meeting will provide a forum for colleagues from academia and industry to connect between disciplines and discuss their own advances and prospects for applying new computational and experimental tools. The aim is for a new generation of muscle researchers to forge close collaboration amongst themselves and bridge the gap between modelers and experimentalists.

Isaac Newton Institute for Mathematical Sciences (INI)

The workshop will explore the use of modern mathematical techniques for the study of problems at the interface between biology and mechanics. It includes the use of machine learning, Baysean methods, and uncertainty quantification for a wide range of problems in biology, physiology, and medicine (biophysics of the cell, brain, the heart, morphogenesis,…)

Molekularbiologie,    Biologie

Isaac Newton Institute for Mathematical Sciences (INI)

This workshop brings together experimental and theoretical researchers who work on cell mechanics, on three different scales. At the microscopic scale, the cytoskeletal active network shapes the cell and generates active forces. At the mesoscale, the collective motion and mechanics of cells gives rises to tissues such as epithelial cell sheets which have become a premier biophysical model system. In the full biological context of cell and developmental mechanics, such as in model tissue organoids, shapes and function arise through the interplay of this active mechanics with morphogens and signalling. Our workshop will explore these three scales of size and complexity, with a view towards bridging the gaps between communities and developing a true multiscale understanding.

Molekularbiologie,    Biologie

The aim of the ICoBT meetings is to bring together researchers from across the scientific, clinical and engineering spectrum, to promote communication across the different disciplines and to provide a platform for the presentation of new work in one meeting focused solely on Biotribology.

orthopaedic surgery, dentistry, biomechanics, biomaterials, soft matter, cosmetic chemistry, biophysics and biomimetics