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Course — Biocatalysis – Solving Scale-Up Issues with Biocatalysed Reactions
19 Jun 2023 - 20 Jun 2023 • Online Platform, Any Location (virtual event)
Organizer:
Scientific Update Ltd.
Abstract:
Many forays by organic chemists into using biocatalysis in chemical synthesis stall at the initial scale-up stage. Screening and small scale (gram) reactions progress as planned, but when scaled -up, reactions stall, take more enzyme than expected, work-ups end up with emulsion issues etc. This course will look at some of the techniques and technologies ( tricks of the trade) that can help derisk scaling up biocatalysed reactions .A further barrier to the adoption of more biocatalytic reactions are production / EHS scientists who are unsure how to handle enzymes in the plant/pilot plant. the course will also look at good sources of information/data to facilitate the use of enzymes at scale.
Event listing ID:
1539029
2
Course — Green Chemistry – Towards More Sustainable Synthesis
09 Oct 2023 - 10 Oct 2023 • Online Platform, Any Location (virtual event)
Organizer:
Scientific Update Ltd.
Abstract:
This Online short course on “Towards more sustainable synthesis” will look at techniques, strategies and tools to minimise the environmental impact of manufacturing pharma/agrochemical & fine chemical intermediates and products.
Event listing ID:
1539136
3
Course — Chemical and Process Safety for Development Chemists
09 Oct 2023 - 17 Oct 2023 • Online Platform, Any Location (virtual event)
Organizer:
Scientific Update Ltd.
Abstract:
In this course, the basics of chemical process safety are explained, always starting from the underlying chemistry. A lot of emphasis will be put on heat and gas evolution, how they affect the inherent process safety and how they can be measured in the lab. Basic scale-up calculations for both gas and heat evolution will be explained using examples and exercises. Guidelines will be given to prevent possible issues with heat transfer at larger scale. The importance of stability data of chemicals, reaction mixtures and products will be explained, together with different tools to determine them experimentally. Background will be provided to understand and interpret the results of reaction calorimetry and thermal stability experiments. Safety aspects of upstream or downstream processes like storage and waste streams will be discussed. The safety benefits of flow chemistry will be explained, and the specific safety evaluation needed for such flow processes will be explored as well.
Event listing ID:
1539135


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Last updated: 19 January 2023