Rapid advancement in the field of NMR spectroscopy in recent years has allowed for the development of novel methods for characterizing biomolecular structure and dynamics. The unique ability of NMR to probe biomolecules under native conditions and near physiological state has enabled researchers to address new problems in biology. This India | EMBO Lecture Course will focus on emerging developments in NMR that will spur further innovation in the areas of protein dynamics, membrane proteins, intrinsically disordered proteins, phase separation, paramagnetic proteins, and large protein complexes. We aim to bring together researchers with diverse interests to realize the full potential of the latest advances in solution and solid-state biomolecular NMR spectroscopy, and to engage early career researchers and leaders in the field in discussions about remaining challenges and the new methods and techniques being developed to address these problems. Bringing together scientists with expertise in different dimensions of NMR will enable facile exchange of ideas, spur collaborative research, and drive future breakthroughs.
This conference is dedicated to the mass spectrometry of membrane proteins using a broad range of approaches. This includes applications to structure, biophysics, expression levels, cellular localization, interactions, and function. In addition, we also propose some talks covering complementary analytical techniques, such as X-ray crystallography, NMR, and cryoEM. We envisage this meeting will be topical for the pharmaceutical industry, since many of the current industrial therapeutic targets are membrane proteins.
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