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SMALP-23 — The First International Conference of Native Membrane Nanoparticles
20 Oct 2023 - 22 Oct 2023 • Knoxville, TN 37996, United States
Prof. Barry D. Bruce, Department of Biochemistry Cell and Molecular Biology
SMALP-23 is the inaugural International Conference that will bring together the leading international scientists investigating this new concept using biochemistry., biophysics, spectroscopy, chemical biology, polymer chemistry, advanced imaging, and cell biology. Examining the composition, assembly, dynamics, and atomic structures of native membrane particles remains technically challenging. This convergence of approaches will move biology from a postgenomic era to a more integrated understanding of how this fundamental unit of membrane function can mediate signal transduction, molecular transport, energy transduction, and protein/lipid trafficking. This young field has been catapulted forward by the ability to isolate these particles using non-detergent extraction methods. Their biological mechanisms and molecular compositions can be resolved using native nanodiscs formed by poly(styrene-co-maleic acid) (SMA) and other related copolymers. These amphipathic polymers rapidly and spontaneously fragment membranes into water-soluble discs holding a bilayer section. This allows structures of complexes found in vivo to be prepared without resorting to synthetic detergents or artificial lipids. Progress in the field demonstrates that polymer-derived particles better represent how biology works in membranes than naked proteins devoid of lipids. SMALP-23 will be a highly interdisciplinary conference that will allow the interaction of disparate disciplines and combine established investigators and young scientists in a stimulating yet informal setting.
Nanoparticles, SMALPS, GPCR, nanodiscs, Lipids, membranes, bilayers
Event listing ID:
1579562 offers, as part of its business activities, a directory of upcoming scientific and technical meetings. The calendar is published for the convenience of conference participants and we strive to support conference organisers who need to publish their upcoming events. Although great care is being taken to ensure the correctness of all entries, we cannot accept any liability that may arise from the presence, absence or incorrectness of any particular information on this website. Always check with the meeting organiser before making arrangements to participate in an event!

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Last updated: 29 September 2023