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European Molecular Biology Organization – EMBO

Meiosis is a defining feature of sexual reproduction. This specialized cell division program comprises a single round of DNA replication followed by two successive cell divisions, thereby reducing chromosome number by half. This reduction accommodates the later combination of two haploid gametes during fertilization to reconstitute a full diploid genome. The unique events of meiosis, including pairwise alignment of parental chromosomes, inter-homolog recombination, kinetochore attachment, cell cycle adaptations and error correction mechanisms, are intensely studied processes in numerous model organisms (fungi, protists, plants, and animals). The Meiosis field is driven by fascination in how evolution has implemented and perfected the meiotic program, and also by its significance to both plant breeding and human health. As a special topic for the 2021 EMBO Workshop, we have chosen homolog pairing. The recognition and physical pairing of homologous chromosomes is an essential feature of meiosis, and also occurs in other contexts. It is therefore timely to bring together the fields of meiotic and post-meiotic chromosome pairing to potentially uncover common principles and mechanisms.

The ReSOLUTE-IMI Consortium

The RESOLUTE and REsolution consortia of the Innovative Medicines Initiative of the European Union have been empowering over the last years the scientific community with novel research tools and datasets for transporters of the Solute Carrier (SLC) supergroup. In 2023, both projects are coming to an end, and we would like to finish with a big celebratory and future-looking conference: “Unlocking Transporters for Drug Discovery”. At the event expect to see presented the results and lessons learned by the RESOLUTE and REsolution consortia over the last five years. Furthermore, top international scientists interested in metabolism and its regulation, drug discovery, the function and structure of membrane proteins will be speaking.

RESOLUTE Communications Manager;     Email: contact@re-solute.eu

transporters, solute carriers, SLC, genomics, metabolomics, proteomics, systems biology, data integration, drug discovery, medicine, variants, mutants, structural biology, resources, bio-tools, cell lines, plasmids

Systems Biology and Computational Biology,    Genomics and Bioinformatics