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Gordon Research Seminar

Metal ions are fundamental to bioinorganic chemistry, playing essential roles in catalyzing biochemical reactions and maintaining metal homeostasis. They are indispensable for sustaining biological processes on Earth. Over the years, researchers have developed a range of scientific tools—including synthetic inorganic chemistry, spectroscopy, structural biology, protein engineering, and computational modeling—to investigate the functions of metals in biological systems. As research advances, new insights continue to emerge, deepening our understanding of the diverse roles and mechanisms of metal ions in life.

Biochemistry and Medicinal Chemistry, Toxicology,    Organometallic Chemistry, Coordination Chemistry

Gordon Research Conference (GRC)

The Metals in Biology GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes an array of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.

Biochemistry and Medicinal Chemistry, Toxicology,    Organometallic Chemistry, Coordination Chemistry

CHI

Join a vibrant community of scientists, trailblazers, and industry leaders at PepTalk 2026, as we mark 25 years of accelerating breakthroughs in biotherapeutic discovery and development. Renowned as one of the most influential events in protein science, PepTalk is where fresh ideas ignite, collaborations flourish, and next-generation solutions take shape.

This year’s expanded agenda features symposia and conference tracks, covering protein expression, production platforms, lab automation for higher throughput, analytical characterization and preformulation strategies for novel modalities, antibody discovery and development, and new this year - expression and development of therapeutic peptides and miniproteins.

Phone: [781.972.5400];     Email: chi@healthtech.com

Keystone Symposia

Biological discovery is undergoing a transformation driven by the convergence of advanced imaging technologies, data science, and computational modeling. This Keystone Symposium will address the critical need to integrate heterogeneous imaging modalities, aided by computational and Deep Learning-driven approaches, to derive mechanistic and predictive insights from complex biological data. The meeting aims to foster dialogue among imaging scientists, computational biologists, data scientists, and systems biologists to define emerging frontiers in data integration, standardization, accessibility, and visualization. Previous conferences have often centered on individual structural biology techniques but have rarely emphasized interdisciplinary approaches. In contrast, this meeting contains a carefully curated program that prioritizes research presentations explicitly focused on integrative approaches, ensuring that the symposium moves beyond acknowledgement to actionable convergence.

Biochemistry, Advanced Imaging, Computational Biology, Structural Biology, Data Science, Artificial Intelligence, Deep Learning, Interdisciplinary Science, Data Integration, Predictive Biology

Biology,    Systems Biology and Computational Biology

Keystone Symposia

Sensory Systems: Interoception and Exteroception brings together leaders across neuroscience, physiology, and systems biology to explore how organisms sense, integrate, and respond to both the external world and internal bodily states. From exteroceptive senses such as touch, taste, olfaction, vision, and hearing to rapidly advancing insights into interoception, this meeting highlights how sensory systems shape perception, behavior, homeostasis, and disease. The program features an emphasis on interoception – how signals from organs such as the gut, heart, and lungs are detected, encoded, and interpreted by the nervous system – revealing new frameworks for understanding behavioral and physiological responses. Sessions also explore somatosensation, chemosensation, mechanosensation, and multisensory integration, linking foundational mechanisms to organism-level outcomes. This meeting will be held jointly with Neurobiology of Appetite Control.

Neurobiology, Neuroscience, Sensory Systems, Molecular Biology, Emerging Technologies,

Neurology,    Biology

Keystone Symposia

Neurodevelopmental disorders (NDDs), including autism, intellectual disability, and epilepsy, arise from disruptions during brain development and pose major challenges to public health. Although advances in genetics have identified hundreds of causal genetic risk factors, identifying convergent mechanisms underlying their pathobiology remains a challenge, which hinders the development of personalized therapies. This meeting addresses the critical gap between emerging insights into causal factors, neurodevelopment, and therapeutic innovation by uniting experts across basic and translational neuroscience. This conference will foster new collaborations between investigators in genetics, functional genomics, developmental neurobiology, and industry. Specific aims include showcasing breakthroughs in single-cell genomics, genome perturbation technologies, gene-environment interactions, and novel therapeutic strategies such as gene replacement therapies and ASOs. Unlike existing meetings that focus separately on neurodevelopment, stem cell models, or therapeutic pipelines, this conference uniquely fuses mechanistic understanding of genetic and environmental causes with translational application. This meeting will be held jointly with Neural Plasticity and Recovery after Traumatic CNS Injury & Stroke.

Neurobiology, Neuroscience, Neurodevelopmental Disorders, Gene Therapy, Translational Research, Functional Genomics, Genetics, Genome Editing, Neurogenomics

Genomics and Bioinformatics,    Neurology

Keystone Symposia

Stroke and traumatic injury are common neurologic disorders and the leading causes for adult-onset disability. Development of therapeutics to improve recovery has been hindered due to a limited understanding of how circuits within the central nervous system (CNS) are affected by injury. Technological advances have enabled interrogation of the CNS with unprecedented resolution. These are being applied to stroke and trauma survivors and to animal models, allowing for a critical re-appraisal of proposed mechanisms of recovery. This knowledge is crucially important as neuromodulation therapies are available for clinical trials, but when and how to apply these to patients are not well understood. This conference will bring together scientists working across species, using diverse approaches, to understand the mechanisms underlying dysfunction and recovery after stroke or injury to the brain or spinal cord. This conference will be unique in its focus on basic and translational science of CNS recovery that brings together researchers working across many disease models and injury types. This meeting will be held jointly with Neurodevelopmental Disorders: Mechanisms and Therapeutics.

Neurobiology, Neuroscience, Brain Injuries, Spinal Cord Injuries, Regeneration and Repair in the Nervous System, Stroke, Translational Research, Neuro Modulation, Neuro Repair, Neuro Tech, Neuroplasticity, TBI Research

Neurology,    Biology

Keystone Symposia

Cancer Immunotherapy: Bridging Basic Research and Clinical Translation brings together immunologists, oncologists, bioengineers, and translational scientists to accelerate the next generation of cancer therapies. The meeting spotlights immune-based approaches spanning foundational discovery to clinical application, highlighting how insights from basic biology are reshaping cancer treatment. Program sessions showcase advances in checkpoint therapies, cellular and engineered immunotherapies, cancer vaccines, and tumor microenvironment, and emphasize how innate and adaptive immune responses can be harnessed and optimized to improve therapeutic outcomes.

Cancer, Immunotherapy, Oncology, Biomedical Engineering, Bioengineering, Therapeutics, Translational Research, Protein Engineering

Biotechnology,    Oncology

Keystone Symposia

Genetic medicines are transforming how we treat cardiovascular disease, unlocking opportunities to correct heart and vascular disorders in ways once thought impossible. Basic scientists, clinicians, industry leaders, and innovators will convene at Genetic Medicines to Treat Cardiovascular Disease to explore how gene therapy, RNA-based approaches, gene editing, and advanced disease models are driving these breakthroughs. The program blends cutting-edge science and real-world translation. Sessions will highlight advances in mechanisms underlying cardiovascular genetics, therapeutic target identification, and novel delivery technologies. Plenary speakers and abstract-selected talks will connect foundational research with translational strategies, offering attendees a holistic view of where the field is headed. Additionally, the program will feature panel discussions focused on the steps leading from basic discovery to translation, commercialization, FDA approval, and navigating the venture capital landscape. Key topics include challenges and opportunities in delivery, efficacy, safety, trial design, long-term and off-target effects of therapies, and ethical and regulatory considerations. The program also includes lessons from preclinical and clinical trials, and professional development challenges for early-career researchers. This meeting also emphasizes interdisciplinary collaboration and career development. Career roundtables provide trainees and early-career investigators with direct access to leaders from academia, biotech, and industry for guidance on scientific and professional growth.

Metabolism, Cardiovascular Genetics, RNA Metabolism, Genetics, Geonomics, Stem Cell Biology, Translational Research, Gene Therapy, RNA Therapeutics, Biotech Innovation

Stem-cell Research & Therapy,    Genomics and Bioinformatics

Keystone Symposia

The Keystone Symposium on Precision Genome Engineering will highlight transformative advances that are reshaping the future of genetic medicine by pushing the boundaries of what is possible with genome editing technologies. As the field evolves from proof-of-concept to therapeutic application, critical questions around efficiency, specificity, safety, delivery, and scalability remain. This conference will address these gaps by convening world leaders and emerging innovators to explore next-generation tools, delivery strategies, integrative technologies, and clinical findings that are redefining genome engineering. What sets this symposium apart is its deep focus on the precision and evolution of genome editing itself—ranging from mechanistic insights to therapeutic design—paired with timely discussions on how AI and delivery systems are accelerating discovery. Attendees will leave with an overview of where the field is headed and how to contribute to its next breakthroughs. This meeting will be held jointly with Targeted Delivery of Nucleic Acid Medicines.

Genetics, Genomics, RNA, CRISPR, Translational Research, Artificial Intelligence, Gene Delivery, Molecular Biology

Genomics and Bioinformatics,    Implementation and Applications of Artificial Intelligence

Keystone Symposia

There have been tremendous advances in developing novel nucleic acid-based strategies for treating human diseases. Recent clinical successes have validated nucleic acid-based platforms, documenting that they can provide life-changing medicines to patients who need them. However, efficient delivery of these nucleic acid payloads to the cell type of interest and the appropriate subcellular compartment still limits their full potential despite significant progress over the past decade. This meeting is designed to bring together scientists from multiple disciplines, all working on delivery of nucleic acid cargos to cells. The meeting will cover the latest designs for viral vectors, lipid nanoparticle systems, virus-like particles, and ligand conjugates to enhance delivery of nucleic acid payloads. This meeting is unique in bringing scientists working on these different strategies for drug delivery into a single venue. Although these strategies have the common goal of enhancing intracellular delivery of nucleic acid cargo they tend to be siloed. A key goal of the meeting is to bring scientists together who have different expertise and perspectives to learn from each other, enabling more rapid and effective solutions for these delivery challenges. This will be a joint conference with the genome engineering meeting, which creates a lot of synergies. The genome engineering will discuss various nucleic acid cargo, while this meeting will focus on delivery technologies for the nucleic acid cargo. This meeting will be held jointly with Precision Genome Engineering: From Laboratory to Clinic.

Genetics, Genomics, RNA, Nucleic Acid Therapeutics, Drug Delivery, Gene Therapy, Viral Vectors, Nanoparticles, Translational Research

Genomics and Bioinformatics,    Pharmacology and Drug Development

Keystone Symposia

Despite newer breakthrough medicines, the burden of diabetes and comorbid conditions – including obesity, cardio-renal disease, and others – continues to rise at an alarming rate. This meeting will explore gaps and challenges pertaining to our understanding of pathobiology and emerging therapeutic approaches that hold promise for addressing unmet clinical needs and reversing the trajectory of disease progression. The conference aims to share knowledge, spark scientific collaboration, and generate new research and development ideas. It will focus on three themes: (1) basic science, including genetic research into disease causation; (2) novel therapeutic targets and strategies, emphasizing non-incretin and disease-modifying approaches; and (3) innovative research and clinical tools. A broad mix of scientists will gather to share data, insights, and forward-thinking concepts. The meeting will bring together established and early-career researchers from diverse fields who infrequently collaborate, creating a unique platform for interaction among academic researchers, industry scientists, and clinical investigators. As the first Keystone meeting of its kind focused on metabolic disease, this forum will span basic research, translational science, and clinical drug development. The ability to hear the latest from, and directly interact with, exceptional scientists in this field is assured. Other aspects of the program will include interactive and multi-disciplinary workshops focusing on lessons from clinical trials and on health disparities.

Metabolism, Cardiovascular, Diabetes, Metabolic Disease, Obesity, Endocrinology, Translational Research, Drug Development, Novel Therapeutics

Human Physiology and Metabolism,    Endocrinology