Conferences  >  Life Sciences  >  Molecular Biology  >  United States

This highly dynamic field combines theoretical, computational, biochemical, physical, and cellular approaches to understand the molecular mechanisms that shape life. The 2023 GRS meeting will focus on recent advances in these areas, which have allowed a better understanding of how proteins shape and power biology. Topics will include protein folding, binding interactions, allostery, evolution, design, cellular signaling, macromolecular organization, and more.

Combining Theory and Experiments to Understand Mechanisms of Function

Launched in 2007, this cross-disciplinary FASEB Science Research Conference (SRC) is focused on endoplasmic reticulum (ER) function and dynamics, and the contribution of ER dysfunction to disease.  The conference brings together cell biologists and disease-oriented researchers, including both trainees and independent investigators. It attracts basic researchers interested in protein folding, protein secretion, cellular stress responses, protein post-translational modification, proteasome dependent protein degradation, and regulation of lipid biosynthesis, as well as researchers focusing on a range of pathologies, including diabetes, neurodegeneration, cancer, and diseases of protein misfolding.

Protein science is continuing a dramatic renaissance with the emergence of ever-more powerful methods of structural biology, computation, and molecular biology. The arena of practical applications of protein science continues to expand explosively. The 2023 Proteins GRC will highlight “complexity in proteins” by bringing together experimental, theoretical and computational biochemists, biophysicists, chemists, chemical biologists, biologists and bioengineers who study the diverse aspects of protein science including protein function, dynamics, thermodynamics and structure using cutting-edge techniques and strategies.

Complexity in Proteins

Understanding the molecular mechanisms of gene expression regulation and their implications in drug development/medicine will be the general theme of the 2023 Nucleic Acids GRS. The meeting will also serve as a platform to discuss recent technical developments in cutting-edge microscopy and next generation sequencing methods employed by nucleic acid researchers.

Mechanism Meets Medicine

The Nucleic Acids Gordon Research Conference (NAGRC) is the premier meeting for exchange of new ideas about the structure and mechanistic behavior of nucleic acids and their cellular processing factors, and the potential applications of innovative developments in RNA and DNA science. Historically, the meeting has provided a powerful forum for synthesizing cutting edge information that leads to ground-breaking discoveries and world-changing technologies. An important feature of the meeting is the inclusion of late-breaking findings and the active participation of early career scientists who are at the forefront of nucleic acid science.

Structural, Functional and Mechanistic Behavior of DNA, RNA and Nucleic Acid Processing Enzymes

The focus of this meeting is to highlight advances in the field of nucleosides, nucleotides, and oligonucleotides. Speakers will discuss chemical biology, synthesis, structure, and therapeutic applications of natural and engineered small molecules and oligomers.

Chemical Biology and Clinical Applications of Nucleosides, Nucleotides and Oligomers

Polyamines in Cancer, Medical Genetics, Aging, Pathogens and Plants

For many years, nucleos(t)ide analogues and nucleic acids have served as cornerstones of drug design and development efforts. The Nucleosides, Nucleotides and Oligonucleotides (NNO) Gordon Research Conference is dedicated to understanding the fundamental chemistry, biology, and technologies for the diagnosis and treatment of various diseases using nucleos(t)ides and nucleic acid analogues. In recent years nucleic acids have seen wide use in chemical biology investigations as well as in the clinic as therapeutics and diagnostics. Emerging areas like CRISPR gene editing and siRNA have been developed due to the extensive efforts of many in the NNO field. The 2023 edition will be the 21st NNO GRC and will reflect the evolution of the field and the current explosive growth of NNO based therapeutics, from its original focus on purine and pyrimidine chemistry and biology, to the much broader current scope.

Chemical Biology of Nucleosides and Nucleic Acids Towards Human Therapeutics

Pharmacology and Drug Development,    Biochemistry and Medicinal Chemistry, Toxicology

UC Santa Barbara, Kavli Institute for Theoretical Physics (KITP)

A long-standing question in the neurobiology of learning is that of timescales. The brain can associate events that are separated by seconds, minutes, hours, days, weeks, or longer. Yet, the known biological mechanisms for inducing changes in the synaptic connections between neurons are driven by neural events that are separated by typically no more than a few tens or hundreds of milliseconds. This conference will convene scientists studying the molecular, cellular, and circuit-level mechanisms used by the brain to bridge the multiple timescales across which events play out in the experience of an individual. The goal will be to assemble an up-to-date understanding of the set of biological mechanisms available in the brain to support associative learning across different timescales. The conference's emphasis on biological mechanisms will complement and support the main program’s more computational focus, and encourage an integrated analysis of statistical learning spanning molecular, cellular, circuit, and behavioral-level phenomena.

Neural Networks and Artificial Intelligence, Machine Learning,    Neurology

Cell Biology and Signalling

BPS - The Biophysical Society

A vast number of biologically important enzymes, transporters, and other molecules require the participation or transport of protons. Because the proton is unique in many respects, its properties and reactions are often quite distinct from those of other ions. Our goal is to include a truly international spectrum of speakers and attendees. The invited speakers include chemists, structural biologists, and physiologists whose expertise encompasses a wide range of topics that are all related to the proton. We hope to encourage new understandings on levels from basic science to biomedical applications.