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BIRS Workshop — Mathematical Methods for Exploring and Analyzing Morphological Shapes across Biological Scales
03 Sep 2023 - 08 Sep 2023 • Banff, Alberta, Canada
Organizer:
Banff International Research Station (BIRS) for Mathematical Innovation and Discovery
Abstract:
The advances in imaging techniques have enabled the access to 3D shapes present in a variety of biological structures: organs, cells, organelles, and proteins. Since biological shapes are related to physiological functions, biomedical analyses are poised to incorporate more morphological data. For example, at the macroscopic scale, characterizing brain morphologies allows clinicians to quantify the progression of Alzheimer's disease. At the microscopic scale, the characterization of protein morphologies allows biologists to understand how these biomolecules react to chemical variations of their environment and helps detect promising pharmacological targets for the treatment of conditions ranging from neurological disorders to several cancers. Therefore, different biological scales ask a common statistical question: how can we build mathematical and statistical descriptions of biological morphologies and their variations? This workshop invites participants from different application fields to exchange mathematical and statistical methods for the study of biological shapes.
Event listing ID:
1499259
2
BIRS Workshop — Mechanics of Cells and Polymer Networks: Bridging Theory, Simulation and Experiment
10 Sep 2023 - 15 Sep 2023 • Banff, Alberta, Canada
Organizer:
Banff International Research Station (BIRS) for Mathematical Innovation and Discovery
Abstract:
The interface between biology and quantitative disciplines including physics, mathematics and engineering is rapidly expanding. This is the result of many factors, but is largely driven by higher resolution spatial and temporal data from cutting edge imaging techniques, and increasing success in applying physical modeling techniques to biological problems. Mechanobiology is an especially rapidly developing field at the quantitative biology interface. This field describes how force is generated in biological systems, how force impacts chemistry, and how force generation is controlled by intracellular signaling pathways. Numerous feedforward and feedback interactions connect forces in cells to the dynamics of proteins and gene expression, resulting in highly nonlinear systems with complex and often non-intuitive behaviours.
Event listing ID:
1499258


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Last updated: 27 July 2022