Conferences  >  Life Sciences  >  Genomics and Bioinformatics  >  Germany

European Molecular Biology Organization – EMBO

Regulation of translation is key in the control of gene expression, playing a critical role in many biological and pathophysiological settings. In the last decade, methodological advances have provided comprehensive insights into cellular transcriptomes and proteomes, however, the systems-wide analysis of translation remained an unsolved experimental challenge. The advent of ‘ribosome-profiling’ provided the methodological basis for comprehensive transcriptome-wide analyses of translation at sub-codon resolution by the precise and high-throughput determination of ribosomal positions on mRNA. Its application in a variety of organisms yielded novel insights into protein synthesis and its dynamic regulation, significantly advancing our understanding of the post-transcriptional regulation of gene expression.

European Molecular Biology Organization – EMBO

This symposium explores the many ways by which the genome is regulated in the brain in order to support neural function and plasticity. The extraordinary complexity of the brain places unique demands on the genome: How are several hundreds of different neural types specified by the same genetic instructions? Does the genome provide information that guides their connectivity? How is neural activity regulated by and how does it affect genome output? We will explore these fundamental questions from the standpoint of transcriptional regulation and chromatin-based processes, including but not limited to histone marks and variants, chromatin topology and folding, coding and noncoding RNAs, transposable elements, and DNA modifications. The conference aims to bring together neuroscientists and experts in genome regulation. It will cover a broad range of experimental approaches and model systems, from biochemistry to single-cell genomics, from worms to human organoids. Overall, the conference will address the impact of genome regulation on unique features of the brain — its excitable nature, exquisite response to the environment and parallel processing capacity — with the longer-term vision of understanding how defective genome regulation can give rise to brain disease.

Interplay between gene regulation and neuronal activity, Genomic regulation of brain plasticity and behaviour, Chromatin variations in the brain, From one genome to many neurons: neurodevelopment and neural diversity

Molecular Biology,    Neurology

ecSeq Bioinformatics GmbH

The purpose of this workshop is to get a deeper understanding in Next-Generation Sequencing (NGS) with a special focus on bioinformatics issues. Advantages and disadvantages of current sequencing technologies and their implications on data analysis will be discovered. The participants will be trained on understanding their own NGS data, finding potential problems/errors therein and finally perform their first downstream analysis (variant calling). In the course we will use a real-life NGS dataset from the current market leader illumina. All workshop attendees will be enabled to perform important first tasks of NGS data analysis themselves. The course layout has been adapted to the needs of beginners in the field of NGS bioinformatics and allows scientists with no or little background in computer science to get a first hands-on experience in this new and fast evolving research topic.

ecSeq Bioinformatics GmbH;     Email: events@ecseq.com

Sequencing, NGS, Variant Calling, illumina, Next-Generation Sequencing, Bioinformatics

ecSeq Bioinformatics GmbH

The purpose of the workshop is to introduce the concepts of bioinformatic pipeline development through the context of the open source Workflow Management System (WMS) Nextflow. The participants will be trained in the scripting, configuration and execution of example analysis pipelines based on current industry best-practices, and learn how to share them with other users. Finally, the participants will apply everything they have learned by implementing their own analysis pipelines from the ground up. By the end of the workshop all attendees will be enabled to build their own scalable, reproducible bioinformatic pipelines which can be run locally, on high-performance computing clusters or even in the cloud. The course layout has been adapted to the needs of beginners in the field of computational biology and allows scientists with little or no background in software development to get a first hands-on experience in this new and fast-evolving area of expertise.

ecSeq Bioinformatics GmbH;     Email: events@ecseq.com

Pipeline development, Bioinformatics, WMS, Nextflow, NGS, Next-Generation Sequencing

Since 2009 the Glyco-Bioinformatics Symposium aims at establishing a network of experts in glycochemistry, biology, bioinformatics and computer sciences. In addition, it provides a platform to discuss the latest outcomes presented by the MIRAGE Commission.

Unparalleled diversity and functionality of the glycome

Molecular Biology,    Scientific Computing and Data Science

ecSeq Bioinformatics GmbH

The purpose of this intense one week summer course is to get a deep understanding in Next-Generation Sequencing (NGS) with a special focus on bioinformatics issues. Advantages and disadvantages of current sequencing technologies and their implications on data analysis will be discovered. You will be trained on understanding NGS data formats and handling potential problems/errors therein. In the summer school we will use a real-life RNA-seq dataset from the current market leader illumina. All students will be enabled to perform important first tasks of NGS data analysis themselves. The layout of the summer school has been adapted to the needs of beginners in the field of NGS bioinformatics and allows scientists with no or little background in computer science to get a first hands-on experience in this new and fast evolving research topic. In the evenings there will be social events, like a conference dinner, or a guided city tour through Berlin. These are always great networking possibilities.

ecSeq Bioinformatics GmbH;     Email: events@ecseq.com

NGS, RNA; Illumina, Next-Generation Sequencing, Sequencing, Bioinformatics, RNA-Seq Data Analysis, DNA Variant Calling

European Molecular Biology Organization – EMBO

European Molecular Biology Laboratory | EMBL

This course will provide training in genome editing and cell engineering in mammalian cells and mouse embryos using the highly efficient CRISPR/Cas9 system. Participants will learn design of CRISPR targets using bioinformatics tools, generation of gene knock-outs/knock-ins, and target validation using the most current technologies.

Molecular Biology,    Biotechnology

This sixth PGE meeting will present a unique opportunity to meet and discuss with colleagues, get updated on the newest developments and insights in plant genome evolution, and will provide unique possibilities to network and discuss collaborations.

Domestication and Evolution of Crops; Decisive Moments and Inventions during Plant Genome Evolution; Polyploidy and Hybridization; Plant Genome Integrity; Climate Adaptation

Botany,    Agronomy, Food Production and Food Chemistry

European Molecular Biology Laboratory | EMBL